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Clostridium Difficile TOXIN B (toxB) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS219588

MBS219588 is specific for Clostridium difficile toxin B. No reaction is observed with toxin A. Clostridium difficile isa gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies… More details

$850 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CLOSTRIDIUM DIFFICILE TOXIN B (toxB), Monoclonal Antibody
Full Product Name
MOUSE ANTI CLOSTRIDIUM DIFFICILE TOXIN B
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Clone Number
5158
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 0.1mg/ml (lot specific)
Specificity
This item is specific for Clostridium difficile toxin B. No reaction is observed with toxin A. Clostridium difficile is a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics.

Toxin B (TcdB) is a large exotoxin. Its role in disease is less well understood than that of toxin A, though it seems clear that TcdB contributes to disease. Both toxins modifies the Ras superfamily of small GTPases via glycosylation, inactivating them and leading to the disruption of vital signaling pathways in the cell.
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
269,712 Da
3D Structure
ModBase 3D Structure for P18177
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Preparation||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Target Species
Bacterial
Applications Tested/Suitable for anti-toxB antibody
ELISA (EIA)
Application Notes for anti-toxB antibody
ELISA: Minimum Dilution: 1/20; Maximum Dilution: 1/200

Other Notes

Small volumes of anti-toxB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for toxB purchase

MBS219588 is an antibody targeting toxB. Also known as MOUSE ANTI CLOSTRIDIUM DIFFICILE TOXIN B. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for toxB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
Toxin B
UniProt Protein Name
Toxin B
Protein Family
UniProt Gene Name
toxB
UniProt Synonym Gene Names
tcdB
UniProt Entry Name
TOXB_PEPDI

UniProt Comments for toxB

Cytotoxin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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