Mouse Anti-SFTPD Monoclonal Antibody – Cat# MBS219620

Staining of frozen pig lung with Mouse anti pig Surfactant Protein D

Surfactant PROTEIN D (SFTPD) Antibody – Mouse Monoclonal

Name: SFTPD Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS219620
Price: 620 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS219620

MBS219620 detects porcine surfactant protein D (pSP-D), a 138kD member of the collectin family of proteins. Surfactant protein D is thought to play a significant role in the innate immune response against microorganisms within the lungs and at other mucosal… More details

$620 / 0.25 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SURFACTANT PROTEIN D (SFTPD), Monoclonal Antibody

Full Product Name

MOUSE ANTI PIG SURFACTANT PROTEIN D

Product Gene Name

anti-SFTPD antibody

Clonality

Monoclonal

Isotype

IgG1

Clone Number

1.7

Host

Mouse

Form/Format

Purified
Purified IgG - liquid

Concentration

IgG concentration 1.0mg/ml (lot specific)

Specificity

This item detects porcine surfactant protein D (pSP-D), a 138kD member of the collectin family of proteins. Surfactant protein D is thought to play a significant role in the innate immune response against microorganisms within the lungs and at other mucosal surfaces. SP-D is a multifunctional protein which binds selectively to saccharides and lipids on microbial surfaces promoting antimicrobial responses and regulating surfactant lipid homeostasis. SP-D expression is induced in lung surfactant in response to aerogenous bacterial infection, and upon binding to bacteria, promotes phagocytosis and antigen presentation by dendritic cells. Recent studies suggest that pSP-D could serve as a serum biomarker specific for bronchopneumonia in pigs.

Preparation and Storage

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Molecular Weight

37,986 Da

3D Structure

ModBase 3D Structure for Q9N1X4

Perservative Stabilisers

0.09% Sodium Azide (NaN3)
Preparation||Purified IgG prepared by affinity chromatography on Protein G

Immunogen

Purified porcine surfactant protein D
Histology Positive Control Tissue||Porcine lung tissue
Fusion Partners||Spleen cells from immunised Balb/c mice were fused with cells of theP3X63Ag.8.653 myeloma cell line.
Buffer Solution||Phosphate buffered saline

Target Species

Pig

Applications Tested/Suitable for anti-SFTPD antibody

Immunohistology Frozen, Immunofluorescence (IF), Immunohistology Paraffin*, Western Blot (WB)

Application Notes for anti-SFTPD antibody

Western Blot: This item detects a band of approximately 138kDa.
Immunohistology - Frozen: Minimum Dilution: 1ug/ml
Immunohistology - Paraffin: Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.

TRIS/EDTA buffer pH8.0 is recommended for this purpose.

Other Notes

Small volumes of anti-SFTPD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SFTPD purchase

MBS219620 is an antibody targeting SFTPD. Also known as MOUSE ANTI PIG SURFACTANT PROTEIN D. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SFTPD. It may not necessarily be applicable to this product.

NCBI GI #

47523028

NCBI GeneID

397198

NCBI Accession #

NP_999275.1

UniProt Primary Accession #

Q9N1X4

UniProt Related Accession #

Q9N1X4

GenBank Nucleotide #

NM_214110.1

NCBI Official Full Name

pulmonary surfactant-associated protein D

NCBI Official Symbol

SFTPD

NCBI Official Synonym Symbols

SP-D; PSP-D

UniProt Protein Name

Pulmonary surfactant-associated protein D

UniProt Synonym Protein Names

Lung surfactant protein D

Protein Family

Pulmonary surfactant-associated protein

UniProt Gene Name

SFTPD

UniProt Synonym Gene Names

PSP-D; SP-D

UniProt Entry Name

SFTPD_PIG

NCBI Protein Information

pulmonary surfactant-associated protein D; lung surfactant protein D; surfactant, pulmonary-associated protein D

UniProt Comments for SFTPD

Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties ().

Research Articles on SFTPD

1. The authors demonstrated that the number and position of glycosylation sites determine viral susceptibility to the neutralizing activity of porcine SP-D.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SFTPD antibody

Reference Product	PubMed Publications
SFTPB antibody	>7 publications with SFTPD and SFTPB
SFTPA antibody	>6 publications with SFTPD and SFTPA
SFTPC antibody	>5 publications with SFTPD and SFTPC
SCGB1A1 antibody	>2 publications with SFTPD and SCGB1A1
SLC34A2 antibody	>1 publications with SFTPD and SLC34A2

Pathways associated with anti-SFTPD antibody

Products by Pathway	Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram

Diseases associated with anti-SFTPD antibody

Disease Name	Pubmed Publications
Lung Diseases Antibodies	>27 publications with SFTPD and Lung Diseases
Respiratory Tract Diseases Antibodies	>27 publications with SFTPD and Respiratory Tract Diseases
Inflammation Antibodies	>16 publications with SFTPD and Inflammation
Lung Injury Antibodies	>9 publications with SFTPD and Lung Injury
Pneumonia Antibodies	>5 publications with SFTPD and Pneumonia
Lung Neoplasms Antibodies	>4 publications with SFTPD and Lung Neoplasms
Respiratory Hypersensitivity Antibodies	>3 publications with SFTPD and Respiratory Hypersensitivity
Cardiovascular Diseases Antibodies	>3 publications with SFTPD and Cardiovascular Diseases
Premature Birth Antibodies	>3 publications with SFTPD and Premature Birth
Respiratory Distress Syndrome, Adult Antibodies	>2 publications with SFTPD and Respiratory Distress Syndrome, Adult

Organs/Tissues associated with anti-SFTPD antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>34 publications with SFTPD and Lung