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CDA Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS128744
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This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CDA, Polyclonal Antibody
Full Product Name
CDA Polyclonal Antibody
Product Gene Name
anti-CDA antibody
Product Synonym Names
CDD
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
146
OMIM
123920
3D Structure
ModBase 3D Structure for P32320
Species
Human
Immunogen
Recombinant protein of human CDA
Calculated Molecular Weight
16kDa

Product Categories/Family for anti-CDA antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CDA antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-CDA antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200

Western Blot (WB) of anti-CDA antibody

Western blot analysis of extracts of various cell lines, using CDA antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Rabbit Anti-CDA Polyclonal Antibody – Cat# MBS128744

Immunofluorescence (IF) of anti-CDA antibody

Immunofluorescence analysis of MCF-7 cells using CDA antibody. Blue: DAPI for nuclear staining.
Rabbit Anti-CDA Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS128744

Other Notes

Small volumes of anti-CDA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDA purchase

MBS128744 is an antibody targeting CDA. Also known as CDA Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CDA. It may not necessarily be applicable to this product.

NCBI GI #
1705718
NCBI GeneID
978
NCBI Accession #
P32320.2
UniProt Primary Accession #
P32320
UniProt Related Accession #
P32320
NCBI Official Full Name
Cytidine deaminase
NCBI Official Synonym Full Names
cytidine deaminase
NCBI Official Symbol
CDA
NCBI Official Synonym Symbols
CDD
UniProt Protein Name
Cytidine deaminase
UniProt Synonym Protein Names
Cytidine aminohydrolase
Protein Family
Calcium-transporting ATPase
UniProt Gene Name
CDA
UniProt Synonym Gene Names
CDD
UniProt Entry Name
CDD_HUMAN
NCBI Protein Information
cytidine deaminase; cytidine aminohydrolase; small cytidine deaminase; cytosine nucleoside deaminase

UniProt Comments for CDA

CDA: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. Belongs to the cytidine and deoxycytidylate deaminase family.

Protein type: Nucleotide Metabolism - pyrimidine; Hydrolase; Xenobiotic Metabolism - drug metabolism - other enzymes; EC 3.5.4.5

Chromosomal Location of Human Ortholog: 1p36.2-p35

Cellular Component: extracellular region; cytosol

Molecular Function: protein homodimerization activity; zinc ion binding; nucleoside binding; cytidine deaminase activity

Biological Process: cell surface receptor linked signal transduction; pyrimidine base metabolic process; cytosine metabolic process; nucleobase, nucleoside and nucleotide metabolic process; pyrimidine nucleoside salvage; cytidine deamination; negative regulation of cell growth; pyrimidine salvage; negative regulation of nucleotide metabolic process; protein homotetramerization
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Research Articles on CDA

1. These results provide suggestive evidence of a favorable effect for the XPD 312Asp/Asp and XPD 751Lys/Lys genotypes with respect to overall survival rates in platinum-treated NSCLC patients

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CDA antibody

 Reference Product  PubMed Publications
 DCK antibody  >74 publications with CDA and DCK
 NT5C2 antibody  >4 publications with CDA and NT5C2
 PNP antibody  >2 publications with CDA and PNP

Pathways associated with anti-CDA antibody

 Products by Pathway  Pathway Diagram
 Drug Metabolism - Other Enzymes Pathway antibodies  Drug Metabolism - Other Enzymes Pathway Diagram
 Drug Metabolism - Other Enzymes Pathway antibodies  Drug Metabolism - Other Enzymes Pathway Diagram
 Fluoropyrimidine Activity Pathway antibodies  Fluoropyrimidine Activity Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Salvage Reactions Pathway antibodies  Pyrimidine Salvage Reactions Pathway Diagram

Diseases associated with anti-CDA antibody

 Disease Name  Pubmed Publications
 Anemia Antibodies  >262 publications with CDA and Anemia
 Anemia, Hemolytic Antibodies  >213 publications with CDA and Anemia, Hemolytic
 Neutropenia Antibodies  >93 publications with CDA and Neutropenia
 Bone Marrow Diseases Antibodies  >91 publications with CDA and Bone Marrow Diseases
 Nervous System Diseases Antibodies  >90 publications with CDA and Nervous System Diseases
 Thrombocytopenia Antibodies  >71 publications with CDA and Thrombocytopenia
 Lung Diseases Antibodies  >67 publications with CDA and Lung Diseases
 Carcinoma Antibodies  >56 publications with CDA and Carcinoma
 Gastrointestinal Diseases Antibodies  >40 publications with CDA and Gastrointestinal Diseases
 Neoplasms, Experimental Antibodies  >39 publications with CDA and Neoplasms, Experimental

Organs/Tissues associated with anti-CDA antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >526 publications with CDA and Blood
 Bone Antibodies  >315 publications with CDA and Bone
 Bone Marrow Antibodies  >235 publications with CDA and Bone Marrow
 Brain Antibodies  >78 publications with CDA and Brain
 Liver Antibodies  >69 publications with CDA and Liver
 Skin Antibodies  >59 publications with CDA and Skin
 Kidney Antibodies  >54 publications with CDA and Kidney
 Lung Antibodies  >45 publications with CDA and Lung
 Spleen Antibodies  >30 publications with CDA and Spleen
 Eye Antibodies  >21 publications with CDA and Eye
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