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CD172a Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS224397

Mouse anti Bovine CD172a antibody, clone CC149 recognizes bovine CD172a, also known as MyD-1 antigen and SIRPA. CD172a is a 55kDa single pass type 1 membrane protein belonging to the family of signal regulatory proteins (SIRP). CD172a has been identified as… More details

$460 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD172a, Monoclonal Antibody
Full Product Name
MOUSE ANTI BOVINE CD172a
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
CC149
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
55,093 Da
3D Structure
ModBase 3D Structure for O46631
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Target Species
Bovine
Applications Tested/Suitable for anti-CD172a antibody
Flow cytometry (FC/FACS)
Application Notes for anti-CD172a antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: 1/100; Maximum Dilution: 1/200

Testing Data #1 of anti-CD172a antibody

Staining of bovine peripheral blood lymphocytes with Mouse anti Bovine CD172a (MBS224397) followed by Goat anti Mouse IgG:FITC (MBS235149)
Mouse Anti-CD172a Monoclonal Antibody – Cat# MBS224397

Testing Data #2 of anti-CD172a antibody

Staining of bovine peripheral blood monocytes with Mouse anti Bovine CD172a:RPE-Cy5 (MBS224386)
Mouse Anti-CD172a Monoclonal Antibody, Testing Data #2 – Cat# MBS224397

Other Notes

Small volumes of anti-CD172a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD172a purchase

MBS224397 is an antibody targeting CD172a. Also known as MOUSE ANTI BOVINE CD172a. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD172a. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tyrosine-protein phosphatase non-receptor type substrate 1
NCBI Official Synonym Full Names
signal-regulatory protein alpha<
NCBI Official Symbol
SIRPA
NCBI Official Synonym Symbols
MYD-1; PTPNS1
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type substrate 1
UniProt Synonym Protein Names
CD172 antigen-like family member A; Inhibitory receptor SHPS-1; MyD-1 antigen; Signal-regulatory protein alpha-1; Sirp-alpha-1; CD_antigen: CD172a
UniProt Gene Name
SIRPA
UniProt Synonym Gene Names
MYD1; PTPNS1; SHPS1; SIRP; SHP substrate 1; SHPS-1; Sirp-alpha-1
UniProt Entry Name
SHPS1_BOVIN
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type substrate 1; CD172 antigen-like family member A; MyD-1 antigen; SHP substrate 1; SHPS-1; inhibitory receptor SHPS-1; protein tyrosine phosphatase, non-receptor type substrate 1; signal-regulatory protein alpha-1; sirp-alpha-1

UniProt Comments for CD172a

Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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