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14-3-3 Theta (YWHAQ) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS225068

Rabbit anti 14-3-3 theta antibody recognizes 14-3-3 theta, also known as 14-3-3 protein T-cell, 14-3-3 protein Tau, Protein HS1 or YWHAQ. 14-3-3 theta is a member of the 14-3-3 family of proteins. 14-3-3 proteins regulate multiple cell signaling pathways… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
14-3-3 Theta (YWHAQ), Polyclonal Antibody
Full Product Name
Rabbit anti 14-3-3 Theta
Product Gene Name
Product Synonym Names
14-3-3 Theta Antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat (Expected from Sequence)
Form/Format
Liquid in phosphate buffered saline with 0.02% sodium azide, 50% glycerol.
Purity/Purification
Purified whole serum by affinity chromatography.
Preparation and Storage
Store at -20 degree C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of despatch
Molecular Weight
27,764 Da
OMIM
609009
3D Structure
ModBase 3D Structure for P27348
Immunogen
Recombinant human 14-3-3 theta
Preperation
Antiserum to 14-3-3 theta was raised by repeated immunization of rabbits with highly purified antigen.
Applications Tested/Suitable for anti-YWHAQ antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-YWHAQ antibody
IHC-Paraffin: 1:50-1:200
WB: 1:500-1:2000

Western Blot (WB) of anti-YWHAQ antibody

Western blot analysis of cell and tissue lysates using Rabbit anti 14-3-3 theta antibody
Rabbit Anti-YWHAQ Polyclonal Antibody – Cat# MBS225068

Immunohistochemistry (IHC) of anti-YWHAQ antibody

Immunohistochemistry of paraffin-embedded mouse heart using Rabbit anti 14-3-3 theta antibody at dilution of 1/100
Rabbit Anti-YWHAQ Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS225068

Other Notes

Small volumes of anti-YWHAQ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for YWHAQ purchase

MBS225068 is an antibody targeting YWHAQ. Also known as Rabbit anti 14-3-3 Theta. Reactive in Human, Mouse, Rat (Expected from Sequence). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for YWHAQ. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
14-3-3 protein theta
NCBI Official Synonym Full Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
NCBI Official Symbol
YWHAQ
NCBI Official Synonym Symbols
1C5; HS1; 14-3-3
UniProt Protein Name
14-3-3 protein theta
UniProt Synonym Protein Names
14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
Protein Family
UniProt Gene Name
YWHAQ
NCBI Protein Information
14-3-3 protein theta

NCBI Summary for YWHAQ

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
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UniProt Comments for YWHAQ

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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