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Interleukin-17 (IL-17A) Dog Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS225408

Recombinant Dog interleukin-17A (IL-17A) is a recombinant protein corresponding to a 127 amino acid sequence of native canine IL-17A.Native canine IL-17A is a 17.7 kDa proinflammatory cytokine belonging to the IL-17 cytokine family and produced by activated T… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Interleukin-17 (IL-17A), Recombinant Protein
Full Product Name
Recombinant Dog Interleukin-17
Product Synonym Names
IL-17A
Host
Pichia pastoris
Species Reactivity
Dog
Form/Format
Lyophilized in phosphate buffered saline with 10% Trahalose.
Purity/Purification
>95% by SDS PAGE analysis
Purified by ion-exchange chromatography
Preparation and Storage
Prior to reconstitution store at -20 degree C. After reconstitution store at -20 degree C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Shelf Life: 12 months from date of despatch
Molecular Weight
14.8 kDa
OMIM
603149
Reconstitution
Reconstitute with 20 ul sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. It is recommend that the vial is gently mixed after reconstitution.
Applications Tested/Suitable for IL-17A recombinant protein
ELISA (EIA), Western Blot (WB)

ELISA (EIA) of IL-17A recombinant protein

Dog Interleukin-17A ELISA: Recombinant Dog interleukin-17A (PDP016) detected using Rabbit anti Dog interleukin-17A as the capture reagent and Rabbit anti Dog interleukin-17A:Biotin as the detection reagent followed by Streptavidin:HRP
Dog IL-17A Recombinant Protein – Cat# MBS225408

Other Notes

Small volumes of IL-17A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-17A purchase

MBS225408 is a recombinant protein targeting IL-17A. Also known as Recombinant Dog Interleukin-17. Reactive in Dog. Host: Pichia pastoris.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-17A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
interleukin-17, partial
NCBI Official Synonym Full Names
interleukin 17A
NCBI Official Symbol
IL17A
NCBI Official Synonym Symbols
IL17; CTLA8; IL-17; CTLA-8; IL-17A
UniProt Protein Name
Interleukin-17A
UniProt Synonym Protein Names
Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8
UniProt Gene Name
IL17A
UniProt Synonym Gene Names
CTLA8; IL17; IL-17; IL-17A; CTLA-8
NCBI Protein Information
interleukin-17A

NCBI Summary for IL-17A

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
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UniProt Comments for IL-17A

Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with IL-17A recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >16 publications with IL-17A and Mixed
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