• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

S1PR5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS240411

Edg8 is a Lysophospholipid/Lysosphingolipid Receptor activated by sphingosine-1-phosphate. Two differently expressed splice variants, 2.4 kb and 5.4 kb, are produced by alternative splicing. More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
S1PR5 / EDG8 / S1P5, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human S1PR5 / EDG8 / S1P5
Product Gene Name
Product Synonym Gene Name
EDG8; S1P5
Product Synonym Names
Anti-S1PR5 / EDG8 / S1P5 Antibody IHC-plus; S1PR5; EDG8; Edg-8; S1P receptor Edg-8; S1P receptor 5; S1P(5) receptor; S1P5; SPPR-1; SPPR-2; Human S1PR5; EDG8; S1P5
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.09% sodium azide.
Purity/Purification
Protein G Purified
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
Molecular Weight
32,279 Da
OMIM
605146
3D Structure
ModBase 3D Structure for Q9H228
Target Species
Human
Immunogen Description
Synthetic peptide from human S1PR5 / EDG8.
Immunogen Type
Synthetic peptide
Immunogen
S1PR5 / EDG8 / S1P5 antibody was raised against synthetic peptide from human S1PR5 / EDG8.
Applications Tested/Suitable for anti-S1PR5 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-S1PR5 antibody
ELISA (1:000 - 1:1000), IHC-P (5 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...

Immunohistochemistry (IHC) of anti-S1PR5 antibody

Anti-S1PR5 / EDG8 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-S1PR5 Polyclonal Antibody – Cat# MBS240411

Immunohistochemistry (IHC) of anti-S1PR5 antibody

Anti-S1PR5 / EDG8 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-S1PR5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS240411

Other Notes

Small volumes of anti-S1PR5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for S1PR5 purchase

MBS240411 is an antibody targeting S1PR5. Also known as Rabbit Polyclonal to Human S1PR5 / EDG8 / S1P5. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for S1PR5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sphingosine 1-phosphate receptor 5
NCBI Official Synonym Full Names
sphingosine-1-phosphate receptor 5
NCBI Official Symbol
S1PR5
NCBI Official Synonym Symbols
EDG8; S1P5; Edg-8; SPPR-1; SPPR-2
UniProt Protein Name
Sphingosine 1-phosphate receptor 5
UniProt Synonym Protein Names
Endothelial differentiation G-protein-coupled receptor 8; Sphingosine 1-phosphate receptor Edg-8; S1P receptor Edg-8
UniProt Gene Name
S1PR5
UniProt Synonym Gene Names
EDG8; S1P receptor 5; S1P5; S1P receptor Edg-8
UniProt Entry Name
S1PR5_HUMAN
NCBI Protein Information
sphingosine 1-phosphate receptor 5; S1P receptor 5; S1P receptor Edg-8; sphingosine 1-phosphate receptor EDG8; sphingosine 1-phosphate receptor Edg-8; endothelial differentiation G-protein-coupled receptor 8; endothelial differentiation, sphingolipid G-protein-coupled receptor, 8

NCBI Summary for S1PR5

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]
Show more

UniProt Comments for S1PR5

EDG8: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins. May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: integral to membrane; plasma membrane

Biological Process: regulation of neuron differentiation
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000