Rabbit Anti-CUL9 Polyclonal Antibody – Cat# MBS240536

Anti-CUL9 / Cullin 9 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.

CUL9 Antibody – Rabbit Polyclonal

Name: CUL9 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS240536
Price: 715 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS240536

MBS240536 is an antibody targeting CUL9. Also known as Rabbit Polyclonal to Human CUL9 / Cullin 9. Reactive in Human. Host: Rabbit. More details

$715 / 0.05 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CUL9 / Cullin 9, Polyclonal Antibody

Full Product Name

Rabbit Polyclonal to Human CUL9 / Cullin 9

Product Gene Name

anti-CUL9 antibody

Product Synonym Names

Anti-CUL9 / Cullin 9 Antibody (C-Terminus) IHC-plus; CUL9; Cullin 9; Cullin-9; CUL-9; H7AP1; RP3-330M21.2; KIAA0708; PARC; UbcH7-associated protein 1; Human CUL9; Cullin 9

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Sterile filtered antiserum, 0.01% sodium azide.

Purity/Purification

Delipidated and defibrinated

Specificity

Amino acids 2503-2517 of Human PARC (C-terminus) coupled to KLH.

Preparation and Storage

+4 degree C or -20 degree C, Avoid repeated freezing and thawing.

Molecular Weight

268,362 Da

OMIM

607489

3D Structure

ModBase 3D Structure for Q8IWT3

Target Species

Human

Immunogen Description

Synthetic peptide from human CUL9 / Cullin 9.

Immunogen Type

Synthetic peptide

Immunogen

CUL9 / Cullin 9 antibody was raised against synthetic peptide from human CUL9 / Cullin 9.

Antigen Modification

C-Terminus

Applications Tested/Suitable for anti-CUL9 antibody

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA)

Application Notes for anti-CUL9 antibody

ELISA (1:2000 - 1:10000), IHC-P (1:500), IP, WB (1:500 - 1:1000)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...

Other Notes

Small volumes of anti-CUL9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CUL9. It may not necessarily be applicable to this product.

NCBI GI #

24307991

NCBI GeneID

23113

NCBI Accession #

NP_055904.1

UniProt Primary Accession #

Q8IWT3

UniProt Secondary Accession #

O75188; Q5TCY3; Q68CP2; Q68D92; Q8N3W9; Q9BU56

UniProt Related Accession #

Q8IWT3

GenBank Nucleotide #

NM_015089.3

NCBI Official Full Name

cullin-9

NCBI Official Synonym Full Names

cullin 9

NCBI Official Symbol

CUL9

NCBI Official Synonym Symbols

PARC; H7AP1

UniProt Protein Name

Cullin-9

UniProt Synonym Protein Names

UbcH7-associated protein 1; p53-associated parkin-like cytoplasmic protein

Protein Family

Cullin

UniProt Gene Name

CUL9

UniProt Synonym Gene Names

H7AP1; KIAA0708; PARC; CUL-9

UniProt Entry Name

CUL9_HUMAN

NCBI Protein Information

cullin-9; CUL-9; UbcH7-associated protein 1; parkin-like cytoplasmic p53 binding protein; p53-associated parkin-like cytoplasmic protein

UniProt Comments for CUL9

PARC: Cytoplasmic anchor protein in p53-associated protein complex. Regulates the subcellular localization of p53 and subsequent function. Seems to be part of an atypical cullin-RING- based E3 ubiquitin-protein ligase complex. In vitro, complexes of CUL9/PARC with either CUL7 or TP53 contain E3 ubiquitin-protein ligase activity. Belongs to the cullin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.3.2.-; Ubiquitin conjugating system; Ubiquitin ligase; Ligase

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: cullin-RING ubiquitin ligase complex; cytoplasm

Molecular Function: protein binding; zinc ion binding; ubiquitin protein ligase binding; ATP binding

Biological Process: ubiquitin-dependent protein catabolic process; protein ubiquitination; regulation of mitosis; microtubule cytoskeleton organization and biogenesis

Research Articles on CUL9

1. the regulation of p53 subcellular localization and apoptosis by PARC as a contributing factor in CDDP resistance in OVCA cells and Ca(2+)/calpain in PARC post-translational processing and chemosensitivity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CUL9 antibody

Reference Product	PubMed Publications
CUL7 antibody	>2 publications with CUL9 and CUL7

Diseases associated with anti-CUL9 antibody

Disease Name	Pubmed Publications
Death Antibodies	>2 publications with CUL9 and Death
Neoplasm Metastasis Antibodies	>1 publications with CUL9 and Neoplasm Metastasis

Organs/Tissues associated with anti-CUL9 antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>1 publications with CUL9 and Liver