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MRGPRX4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242712

MRGX4 is an Orphan-A GPCR with an unknown ligand highly similar to other MRG receptors. MRGX4 has been suggested to function in sensory neuron regulation and in the modulation of nociception. More details

$630 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MRGPRX4 / MRGX4, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human MRGPRX4 / MRGX4
Product Gene Name
Product Synonym Gene Name
MRGX4
Product Synonym Names
Anti-MRGPRX4 / MRGX4 Antibody (C-Terminus) IHC-plus; MRGPRX4; MRGX4; SNSR6; SNSR5; MAS-related GPR; member X4; Human MRGPRX4; MRGX4
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human MRGPRX4 / MRGX4. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MRGPRX3 (67%), MRGPRX1 (67%), ALMS1 (44%).
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
36,461 Da
OMIM
607230
3D Structure
ModBase 3D Structure for Q96LA9
Target Species
Human
Immunogen Description
Synthetic 18 amino acid peptide from C-terminus of human MRGPRX4 / MRGX4. Percent identity with other species by BLAST analysis: Human (100%); Gorilla (89%).
Immunogen Type
Synthetic peptide
Immunogen
MRGPRX4 / MRGX4 antibody was raised against synthetic 18 amino acid peptide from C-terminus of human MRGPRX4 / MRGX4. Percent identity with other species by BLAST analysis: Human (100%); Gorilla (89%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-MRGPRX4 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-MRGPRX4 antibody
IHC-P (3 - 16 ug/ml)

Immunohistochemistry (IHC) of anti-MRGPRX4 antibody

Anti-MRGPRX4 / MRGX4 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-MRGPRX4 Polyclonal Antibody – Cat# MBS242712

Immunohistochemistry (IHC) of anti-MRGPRX4 antibody

Anti-MRGPRX4 / MRGX4 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-MRGPRX4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242712

Immunohistochemistry (IHC) of anti-MRGPRX4 antibody

Anti-MRGPRX4 / MRGX4 antibody IHC of human spinal cord, dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-MRGPRX4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242712

Immunohistochemistry (IHC) of anti-MRGPRX4 antibody

Anti-MRGPRX4 / MRGX4 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-MRGPRX4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242712

Other Notes

Small volumes of anti-MRGPRX4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MRGPRX4 purchase

MBS242712 is an antibody targeting MRGPRX4. Also known as Rabbit Polyclonal to Human MRGPRX4 / MRGX4. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MRGPRX4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
mas-related G-protein coupled receptor member X4
NCBI Official Synonym Full Names
MAS-related GPR, member X4
NCBI Official Symbol
MRGPRX4
NCBI Official Synonym Symbols
GPCR; MRGX4; SNSR6
UniProt Protein Name
Mas-related G-protein coupled receptor member X4
UniProt Synonym Protein Names
Sensory neuron-specific G-protein coupled receptor 5/6
UniProt Gene Name
MRGPRX4
UniProt Synonym Gene Names
MRGX4; SNSR5; SNSR6
UniProt Entry Name
MRGX4_HUMAN
NCBI Protein Information
mas-related G-protein coupled receptor member X4; G protein-coupled receptor MRGX4; G protein-coupled receptor SNSR5; G protein-coupled receptor SNSR6; sensory neuron-specific G-protein coupled receptor 5/6

UniProt Comments for MRGPRX4

MRGPRX4: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins. Belongs to the G-protein coupled receptor 1 family. Mas subfamily.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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