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THRSP Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242761

S14 (Thyroid Hormone Inducible Hepatic Protein) is a nuclear protein communicates the status of dietary fuels and fuel-related hormones to genes required for long-chain fatty acid synthesis. In mammary glands S14 is important for both epithelial proliferation… More details

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Product Overview

Product Name
THRSP, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human THRSP
Product Gene Name
Product Synonym Names
Anti-THRSP Antibody IHC-plus; THRSP; Lpgp; Lipogenic protein 1; S14; SPOT14; THRP; SPOT14 homolog; LPGP1; Spot 14 protein; Thyroid hormone responsive; Human THRSP
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human
Predicted Reactivity: Gorilla (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human THRSP.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
16,561 Da
OMIM
601926
3D Structure
ModBase 3D Structure for Q92748
Target Species
Human
Immunogen Description
Synthetic peptide from human THRSP. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (93%), Monkey (86%).
Immunogen
THRSP antibody was raised against synthetic peptide from human THRSP. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (93%), Monkey (86%).
Applications Tested/Suitable for anti-THRSP antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-THRSP antibody
IHC-P (3.75 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-THRSP antibody

Anti-THRSP antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-THRSP Polyclonal Antibody – Cat# MBS242761

Immunohistochemistry (IHC) of anti-THRSP antibody

Anti-THRSP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-THRSP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242761

Other Notes

Small volumes of anti-THRSP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for THRSP purchase

MBS242761 is an antibody targeting THRSP. Also known as Goat Polyclonal to Human THRSP. Reactive in Human
Predicted Reactivity: Gorilla (at least 90% immunogen sequence identity). Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for THRSP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thyroid hormone-inducible hepatic protein
NCBI Official Synonym Full Names
thyroid hormone responsive
NCBI Official Symbol
THRSP
NCBI Official Synonym Symbols
S14; Lpgp; THRP; LPGP1; SPOT14
UniProt Protein Name
Thyroid hormone-inducible hepatic protein
UniProt Synonym Protein Names
Spot 14 protein; S14; SPOT14
UniProt Gene Name
THRSP
UniProt Synonym Gene Names
S14; SPOT14
UniProt Entry Name
THRSP_HUMAN
NCBI Protein Information
thyroid hormone-inducible hepatic protein; SPOT14 homolog; spot 14 protein; lipogenic protein 1; thyroid hormone responsive SPOT14; thyroid hormone responsive (SPOT14 homolog, rat)

NCBI Summary for THRSP

The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and adipose tissue and is controlled by nutritional and hormonal factors. This gene has been shown to be expressed in liver and adipocytes, particularly in lipomatous modules. It is also found to be expressed in lipogenic breast cancers, which suggests a role in controlling tumor lipid metabolism. [provided by RefSeq, Jul 2008]
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UniProt Comments for THRSP

THRSP: Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB. Belongs to the SPOT14 family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 11q14.1

Cellular Component: nucleoplasm; cytosol

Molecular Function: protein homodimerization activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; lipid metabolic process; regulation of lipid biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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