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FMO5 cDNA Clone – Flavin Containing Monooxygenase 5 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1273338

MBS1273338 is a cDNA clone targeting FMO5. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FMO5, cDNA Clone
Full Product Name
FMO5 cDNA Clone
Product Gene Name
FMO5 cdna clone
Sequence
atgactaaga aaagaattgc tgtgattggg ggaggagtga gcgggctctc ttccatcaag tgctgcgtag aagaaggctt ggaacctgtc tgctttgaaa ggactgatga catcggaggg ctctggaggt tccaggaaaa tcctgaagaa ggaagggcca gtatttacaa atcagtgatc atcaatactt ctaaagagat gatgtgcttc agtgactatc caatcccaga tcattatccc aacttcatgc ataatgccca ggtcctggag tatttcagga tgtatgccaa agaatttgac cttctaaagt atattcgatt taagaccact gtgtgcagtg tgaagaagca gcctgatttt gccacttcag gccaatggga agtggtcact gaatctgaag ggaaaaagga gatgaatgtc tttgatggag tcatggtttg cactggccat cacaccaatg ctcatctacc tctggaaagc ttccctggaa ttgagaagtt caaagggcag tacttccaca gtcgagacta taagaaccca gagggattca ctggaaagag agtcattata attggcattg ggaattctgg aggggatctg gctgtagaga ttagccaaac agccaagcag gttttcctca gcaccaggag aggggcttgg atcctgaatc gtgtagggga ctacggatat cctgctgatg tgttgttctc ttctcgactt acacatttta tatggaagat ctgtggccaa tcattagcaa acaaatattt ggaaaaaaag ataaaccaaa ggtttgacca tgaaatgttt ggcctgaagc ctaaacacag gtctaaagac attgccctca cagagtga
Molecular Weight
52,477 Da
OMIM
603957
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FMO5 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FMO5. It may not necessarily be applicable to this product.

NCBI GI #
23274233
NCBI GeneID
2330
NCBI Accession #
BC035687
UniProt Secondary Accession #
Q8IV22; B2RBG1; C9JJD1
UniProt Related Accession #
P49326
NCBI Official Full Name
Homo sapiens flavin containing monooxygenase 5, mRNA
NCBI Official Synonym Full Names
flavin containing monooxygenase 5
NCBI Official Symbol
FMO5
UniProt Protein Name
Dimethylaniline monooxygenase [N-oxide-forming] 5
UniProt Synonym Protein Names
Dimethylaniline oxidase 5; Hepatic flavin-containing monooxygenase 5; FMO 5
Protein Family
Dimethylaniline monooxygenase
UniProt Gene Name
FMO5
UniProt Synonym Gene Names
FMO 5
UniProt Entry Name
FMO5_HUMAN
NCBI Protein Information
dimethylaniline monooxygenase [N-oxide-forming] 5

NCBI Summary for FMO5

Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
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UniProt Comments for FMO5

FMO5: In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme. Belongs to the FMO family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Xenobiotic Metabolism - drug metabolism - cytochrome P450; Oxidoreductase; EC 1.14.13.8

Chromosomal Location of Human Ortholog: 1q21.1

Cellular Component: cytoplasm; endoplasmic reticulum

Molecular Function: flavin-containing monooxygenase activity

Biological Process: drug metabolic process
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Research Articles on FMO5

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FMO5 cdna clone

 Products by Pathway  Pathway Diagram
 Catalytic Cycle Of Mammalian FMOs Pathway antibodies  Catalytic Cycle Of Mammalian FMOs Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Metapathway Biotransformation antibodies  Metapathway Biotransformation Diagram
 Nicotine Degradation IV Pathway antibodies  Nicotine Degradation IV Pathway Diagram

Diseases associated with FMO5 cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with FMO5 and Neoplasms
 Drug Toxicity Antibodies  >3 publications with FMO5 and Drug Toxicity
 Breast Neoplasms Antibodies  >2 publications with FMO5 and Breast Neoplasms
 Liver Diseases Antibodies  >2 publications with FMO5 and Liver Diseases
 Heart Diseases Antibodies  >1 publications with FMO5 and Heart Diseases
 Kidney Diseases Antibodies  >1 publications with FMO5 and Kidney Diseases
 Cardiovascular Diseases Antibodies  >1 publications with FMO5 and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >1 publications with FMO5 and Neoplasms, Experimental
 Carcinoma Antibodies  >1 publications with FMO5 and Carcinoma
 Liver Neoplasms Antibodies  >1 publications with FMO5 and Liver Neoplasms

Organs/Tissues associated with FMO5 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >47 publications with FMO5 and Liver
 Kidney Antibodies  >11 publications with FMO5 and Kidney
 Brain Antibodies  >4 publications with FMO5 and Brain
 Intestine Antibodies  >3 publications with FMO5 and Intestine
 Uterus Antibodies  >2 publications with FMO5 and Uterus
 Heart Antibodies  >2 publications with FMO5 and Heart
 Testis Antibodies  >2 publications with FMO5 and Testis
 Mammary Gland Antibodies  >1 publications with FMO5 and Mammary Gland
 Spleen Antibodies  >1 publications with FMO5 and Spleen
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