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TRERF1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242938

MBS242938 is an antibody targeting TRERF1. Also known as Rabbit Polyclonal (IgG) to Human TRERF1. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TRERF1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human TRERF1
Product Gene Name
anti-TRERF1 antibody
Product Synonym Names
Anti-TRERF1 Antibody (aa1071-1120) IHC-plus; TRERF1; DJ139D8.5; HSA277276; Rapa-1; Rapa-2; RP1-139D8.5; BCAR2; TReP-132; Zinc finger protein rapa; RAPA; TREP132; Human TRERF1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
TREF1 Antibody detects endogenous levels of total TREF1 protein.
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
124,999 Da
OMIM
610322
3D Structure
ModBase 3D Structure for Q96PN7
Target Species
Human
Immunogen Description
Synthetic peptide from human TREF1 (aa1071-1120).
Immunogen
TRERF1 antibody was raised against synthetic peptide from human TREF1 (aa1071-1120).
Antigen Modification
aa1071-1120
Applications Tested/Suitable for anti-TRERF1 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-TRERF1 antibody
ELISA (1:1000), IHC-P (5 ug/ml)

Immunohistochemistry (IHC) of anti-TRERF1 antibody

Anti-TRERF1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Rabbit Anti-TRERF1 Polyclonal Antibody – Cat# MBS242938

Other Notes

Small volumes of anti-TRERF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRERF1. It may not necessarily be applicable to this product.

NCBI GI #
15812226
NCBI GeneID
55809
NCBI Accession #
NP_277037.1
UniProt Primary Accession #
Q96PN7
UniProt Secondary Accession #
Q05GC6; Q7Z6T2; Q7Z6T3; Q9NQ72; Q9NQ73; Q9NUN9
UniProt Related Accession #
Q96PN7
GenBank Nucleotide #
NM_033502.3
NCBI Official Full Name
transcriptional-regulating factor 1 isoform 2
NCBI Official Synonym Full Names
transcriptional regulating factor 1
NCBI Official Symbol
TRERF1
NCBI Official Synonym Symbols
RAPA; BCAR2; TREP132; TReP-132; HSA277276; dJ139D8.5
UniProt Protein Name
Transcriptional-regulating factor 1
UniProt Synonym Protein Names
Breast cancer anti-estrogen resistance 2; Transcriptional-regulating protein 132; Zinc finger protein rapa; Zinc finger transcription factor TReP-132
Protein Family
Transcriptional-regulating factor
UniProt Gene Name
TRERF1
UniProt Synonym Gene Names
BCAR2; RAPA; TREP132
UniProt Entry Name
TREF1_HUMAN
NCBI Protein Information
transcriptional-regulating factor 1; rapa-1; rapa-2; zinc finger protein rapa; transcriptional regulating protein 132; transcriptional-regulating protein 132; breast cancer anti-estrogen resistance 2; zinc finger transcription factor TReP-132

NCBI Summary for TRERF1

This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

UniProt Comments for TRERF1

TReP-132: Binds DNA and activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1

Protein type: Nuclear receptor co-regulator; Transcription factor; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 6p21.1-p12.1

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: ligand-dependent nuclear receptor transcription coactivator activity; metal ion binding; chromatin binding; transcription factor binding; DNA bending activity; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; homeostatic process; multicellular organismal development; positive regulation of transcription, DNA-dependent; cholesterol catabolic process; steroid biosynthetic process; regulation of hormone biosynthetic process
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Research Articles on TRERF1

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TRERF1 antibody

 Reference Product  PubMed Publications
 NR5A1 antibody  >5 publications with TRERF1 and NR5A1
 CDKN1B antibody  >2 publications with TRERF1 and CDKN1B
 EP300 antibody  >1 publications with TRERF1 and EP300
 CYP17A1 antibody  >1 publications with TRERF1 and CYP17A1

Diseases associated with anti-TRERF1 antibody

 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >4 publications with TRERF1 and Skin Diseases
 Breast Neoplasms Antibodies  >4 publications with TRERF1 and Breast Neoplasms
 Carcinoma Antibodies  >2 publications with TRERF1 and Carcinoma
 Adenocarcinoma Antibodies  >1 publications with TRERF1 and Adenocarcinoma
 Kidney Diseases Antibodies  >1 publications with TRERF1 and Kidney Diseases

Organs/Tissues associated with anti-TRERF1 antibody

 Organ/Tissue Name  Pubmed Publications
 Adrenal Gland Antibodies  >4 publications with TRERF1 and Adrenal Gland
 Testis Antibodies  >4 publications with TRERF1 and Testis
 Thymus Antibodies  >3 publications with TRERF1 and Thymus
 Lymph Node Antibodies  >1 publications with TRERF1 and Lymph Node
 Ganglia Antibodies  >1 publications with TRERF1 and Ganglia
 Mammary Gland Antibodies  >1 publications with TRERF1 and Mammary Gland
 Placenta Antibodies  >1 publications with TRERF1 and Placenta
 Kidney Antibodies  >1 publications with TRERF1 and Kidney
 Brain Antibodies  >1 publications with TRERF1 and Brain
 Embryonic Tissue Antibodies  >1 publications with TRERF1 and Embryonic Tissue
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