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SREB Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243206

GPR85, a member of the SREB (Super-Conserved Receptor Expressed in Brain) family of GPCRs, is an Orphan-A GPCR with an unknown ligand. The rat counterpart of SREB2 is involved in the development of the cerebral cortex. More details

$630 / 0.05 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
SREB / GPR85, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human SREB / GPR85
Product Gene Name
Product Synonym Gene Name
GPR85
Product Synonym Names
Anti-SREB / GPR85 Antibody (Extracellular Domain) IHC-plus; GPR85; G protein-coupled receptor 85; Rgpr85; SREB; Pkrcx1; SREB2; Human SREB; GPR85
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Chicken, Xenopus, Human, Mouse, Orangutan, Rat, Zebrafish
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GPR85. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
41,995 Da
OMIM
605188
3D Structure
ModBase 3D Structure for P60893
Target Species
Human
Immunogen Description
Synthetic 20 amino acid peptide from 2nd extracellular domain of human GPR85. Percent identity with other species by BLAST analysis: Human, Orangutan, Mouse, Rat, Turkey, Chicken, Lizard, Xenopus, Seabass, Stickleback, Pufferfish, Zebrafish (100%).
Immunogen Type
Synthetic peptide
Immunogen
SREB / GPR85 antibody was raised against synthetic 20 amino acid peptide from 2nd extracellular domain of human GPR85. Percent identity with other species by BLAST analysis: Human, Orangutan, Mouse, Rat, Turkey, Chicken, Lizard, Xenopus, Seabass, Stickleback, Pufferfish, Zebrafish (100%).
Antigen Modification
Extracellular Domain
Applications Tested/Suitable for anti-SREB antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-SREB antibody
IHC-P (5.5 ug/ml)

Immunohistochemistry (IHC) of anti-SREB antibody

Anti-GPR85 antibody IHC of human putamen, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-SREB Polyclonal Antibody – Cat# MBS243206

Other Notes

Small volumes of anti-SREB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SREB purchase

MBS243206 is an antibody targeting SREB. Also known as Rabbit Polyclonal to Human SREB / GPR85. Reactive in Chicken, Xenopus, Human, Mouse, Orangutan, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SREB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
probable G-protein coupled receptor 85
NCBI Official Synonym Full Names
G protein-coupled receptor 85
NCBI Official Symbol
GPR85
NCBI Official Synonym Symbols
SREB; SREB2
UniProt Protein Name
Probable G-protein coupled receptor 85
UniProt Synonym Protein Names
Super conserved receptor expressed in brain 2
UniProt Gene Name
GPR85
UniProt Synonym Gene Names
SREB2
UniProt Entry Name
GPR85_HUMAN
NCBI Protein Information
probable G-protein coupled receptor 85; seven transmembrane helix receptor; super conserved receptor expressed in brain 2

NCBI Summary for SREB

Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]).[supplied by OMIM, Aug 2008]
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UniProt Comments for SREB

GPR85: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q31

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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