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SCRN1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243433

MBS243433 is an antibody targeting SCRN1. Also known as Rabbit Polyclonal to Human SCRN1 / Secernin 1. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
SCRN1 / Secernin 1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human SCRN1 / Secernin 1
Product Gene Name
Product Synonym Names
Anti-SCRN1 / Secernin 1 Antibody (C-Terminus) IHC-plus; SCRN1; KIAA0193; Secernin-1; SES1; Secernin 1; Human SCRN1; Secernin 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human SCRN1
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
38,864 Da
OMIM
614965
3D Structure
ModBase 3D Structure for Q12765
Target Species
Human
Immunogen Description
A 20 amino acid peptide near the carboxy terminus of human SCRN1.
Immunogen Type
Synthetic peptide
Immunogen
SCRN1 / Secernin 1 antibody was raised against a 20 amino acid peptide near the carboxy terminus of human SCRN1.
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-SCRN1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-SCRN1 antibody
ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: SCRN1 antibody can be used for detection of SCRN1 by Western blot at 1-2 ug/ml.

Immunohistochemistry (IHC) of anti-SCRN1 antibody

Anti-SCRN1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-SCRN1 Polyclonal Antibody – Cat# MBS243433

Immunohistochemistry (IHC) of anti-SCRN1 antibody

Anti-SCRN1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-SCRN1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243433

Immunofluorescence (IF) of anti-SCRN1 antibody

Immunofluorescence of SCRN1 in Human Kidney cells with SCRN1 antibody at 20 ug/ml.
Rabbit Anti-SCRN1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS243433

Western Blot (WB) of anti-SCRN1 antibody

Western blot analysis of SCRN1 in human kidney tissue lysate with SCRN1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-SCRN1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS243433

Other Notes

Small volumes of anti-SCRN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SCRN1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
secernin-1 isoform a
NCBI Official Synonym Full Names
secernin 1
NCBI Official Symbol
SCRN1
NCBI Official Synonym Symbols
SES1
UniProt Protein Name
Secernin-1
Protein Family
UniProt Gene Name
SCRN1
UniProt Synonym Gene Names
KIAA0193
UniProt Entry Name
SCRN1_HUMAN
NCBI Protein Information
secernin-1

NCBI Summary for SCRN1

This gene likely encodes a member of the secernin family of proteins. A similar protein in rat functions in regulation of exocytosis in mast cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

UniProt Comments for SCRN1

SCRN1: Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium. Belongs to the peptidase C69 family. Secernin subfamily.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 7p14.3

Cellular Component: nuclear membrane; cytoplasm; nucleus

Molecular Function: dipeptidase activity

Biological Process: exocytosis; proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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