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SLC16A7 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243657

MBS243657 is an antibody targeting SLC16A7. Also known as Goat Polyclonal to Human SLC16A7 / MCT2. Reactive in Gibbon, Gorilla, HumanPredicted Reactivity: Monkey (at least 90% immunogen sequence identity). Host: Goat. More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SLC16A7 / MCT2, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human SLC16A7 / MCT2
Product Gene Name
anti-SLC16A7 antibody
Product Synonym Gene Name
MCT2
Product Synonym Names
Anti-SLC16A7 / MCT2 Antibody (C-Terminus) IHC-plus; SLC16A7; MCT 2; Monocarboxylate transporter 2; MCT2; Human SLC16A7; MCT2
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gibbon, Gorilla, Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human SLC16A7.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
52,200 Da
OMIM
603654
3D Structure
ModBase 3D Structure for O60669
Target Species
Human
Immunogen Description
Synthetic peptide C-SNAQSVTSERETNI from the C-terminus of human SLC16A7 (NP_004722.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Marmoset (93%); Monkey (86%).
Immunogen Type
Synthetic peptide
Immunogen
SLC16A7 / MCT2 antibody was raised against synthetic peptide C-SNAQSVTSERETNI from the C-terminus of human SLC16A7 (NP_004722.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Marmoset (93%); Monkey (86%).
Antigen Modification
C-Terminus

Product Categories/Family for anti-SLC16A7 antibody

Family: Transporter; Subfamily: Monocarboxylic acid transporter
Applications Tested/Suitable for anti-SLC16A7 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-SLC16A7 antibody
ELISA (1:128000), IHC-P (2.5 - 3.75 ug/ml), WB (1:128000, 1 - 3 ug/ml)

Immunohistochemistry (IHC) of anti-SLC16A7 antibody

Anti-SLC16A7 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Goat Anti-SLC16A7 Polyclonal Antibody – Cat# MBS243657

Western Blot (WB) of anti-SLC16A7 antibody

Antibody (1 ug/ml) staining of A549 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-SLC16A7 Polyclonal Antibody, Western Blot (WB) – Cat# MBS243657

Other Notes

Small volumes of anti-SLC16A7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC16A7. It may not necessarily be applicable to this product.

NCBI GI #
24431958
NCBI GeneID
9194
NCBI Accession #
NP_004722.2
UniProt Primary Accession #
O60669
UniProt Secondary Accession #
Q8NEM3; Q9UPB3
UniProt Related Accession #
O60669
GenBank Nucleotide #
NM_004731.4
NCBI Official Full Name
monocarboxylate transporter 2
NCBI Official Synonym Full Names
solute carrier family 16 (monocarboxylate transporter), member 7
NCBI Official Symbol
SLC16A7
NCBI Official Synonym Symbols
MCT2
UniProt Protein Name
Monocarboxylate transporter 2
UniProt Synonym Protein Names
Solute carrier family 16 member 7
Protein Family
Monocarboxylate transporter
UniProt Gene Name
SLC16A7
UniProt Synonym Gene Names
MCT2; MCT 2
UniProt Entry Name
MOT2_HUMAN
NCBI Protein Information
monocarboxylate transporter 2; solute carrier family 16, member 7 (monocarboxylic acid transporter 2)

NCBI Summary for SLC16A7

This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
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UniProt Comments for SLC16A7

SLC16A7: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: pyruvate secondary active transmembrane transporter activity; symporter activity; lactate transmembrane transporter activity; secondary active monocarboxylate transmembrane transporter activity; pyruvate transmembrane transporter activity

Biological Process: transmembrane transport
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Research Articles on SLC16A7

1. this study provided evidence for the presence of MCT2 in prostate cancer, selectively labeling malignant glands.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC16A7 antibody

 Reference Product  PubMed Publications
 EMB antibody  >4 publications with SLC16A7 and EMB
 BSG antibody  >3 publications with SLC16A7 and BSG
 TNF antibody  >1 publications with SLC16A7 and TNF

Pathways associated with anti-SLC16A7 antibody

 Products by Pathway  Pathway Diagram
 Proton-coupled Monocarboxylate Transport Pathway antibodies  Proton-coupled Monocarboxylate Transport Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram

Diseases associated with anti-SLC16A7 antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >7 publications with SLC16A7 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >5 publications with SLC16A7 and Cardiovascular Diseases
 Necrosis Antibodies  >5 publications with SLC16A7 and Necrosis
 Obesity Antibodies  >3 publications with SLC16A7 and Obesity
 Liver Diseases Antibodies  >2 publications with SLC16A7 and Liver Diseases
 Seizures Antibodies  >2 publications with SLC16A7 and Seizures
 Prenatal Injuries Antibodies  >1 publications with SLC16A7 and Prenatal Injuries
 Liver Neoplasms Antibodies  >1 publications with SLC16A7 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with SLC16A7 and Carcinoma, Hepatocellular
 Lung Diseases Antibodies  >1 publications with SLC16A7 and Lung Diseases

Organs/Tissues associated with anti-SLC16A7 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >55 publications with SLC16A7 and Brain
 Blood Antibodies  >35 publications with SLC16A7 and Blood
 Kidney Antibodies  >10 publications with SLC16A7 and Kidney
 Testis Antibodies  >5 publications with SLC16A7 and Testis
 Connective Tissue Antibodies  >1 publications with SLC16A7 and Connective Tissue
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