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TPTE Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244246

The human TPTE is a putative transmembrane tyrosine phosphatase of the PTEN group, and has been suggested to affect signal transduction pathways of the endocrine and/or the spermatogenetic function of the testis. Human TPTE exists in multiple copies and have… More details

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Product Overview

Product Name
TPTE, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human TPTE
Product Gene Name
Product Synonym Names
Anti-TPTE Antibody (Internal) IHC-plus; TPTE; Cancer/testis antigen 44; CT44; PTEN2; Tumor antigen BJ-HCC-5; Human TPTE
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human
Predicted Reactivity: Gibbon (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human TPTE. This antibody is expected to recognise all reported isoforms (NP_954870.2, NP_954868.1 and NP_954869.1). It may cross-react with the almost identical TPTE2 (GeneID 93492; NP_570141.2, NP_954864.1, NP_954863.1).
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
49,344 Da
OMIM
604336
3D Structure
ModBase 3D Structure for P56180
Target Species
Human
Immunogen Description
Synthetic peptide C-ERRTDKTHSEKFQ from an internal region of human TPTE (NP_954870.2; NP_954868.1; NP_954869.1). Percent identity with other species by BLAST analysis: Human (100%), Gibbon (92%), Monkey (85%), Marmoset (85%).
Immunogen Type
Synthetic peptide
Immunogen
TPTE antibody was raised against synthetic peptide C-ERRTDKTHSEKFQ from an internal region of human TPTE (NP_954870.2; NP_954868.1; NP_954869.1). Percent identity with other species by BLAST analysis: Human (100%), Gibbon (92%), Monkey (85%), Marmoset (85%).
Antigen Modification
Internal
Applications Tested/Suitable for anti-TPTE antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-TPTE antibody
ELISA (1:16000), IHC-P (2.5 - 3.75 ug/ml), WB (1:16000, 1 - 3 ug/ml)

Immunohistochemistry (IHC) of anti-TPTE antibody

Anti-TPTE antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Goat Anti-TPTE Polyclonal Antibody – Cat# MBS244246

Western Blot (WB) of anti-TPTE antibody

Antibody (1 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-TPTE Polyclonal Antibody, Western Blot (WB) – Cat# MBS244246

Other Notes

Small volumes of anti-TPTE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TPTE purchase

MBS244246 is an antibody targeting TPTE. Also known as Goat Polyclonal to Human TPTE. Reactive in Human
Predicted Reactivity: Gibbon (at least 90% immunogen sequence identity). Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for TPTE. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
putative tyrosine-protein phosphatase TPTE isoform alpha
NCBI Official Synonym Full Names
transmembrane phosphatase with tensin homology
NCBI Official Symbol
TPTE
NCBI Official Synonym Symbols
CT44; PTEN2
UniProt Protein Name
Putative tyrosine-protein phosphatase TPTE
UniProt Synonym Protein Names
Cancer/testis antigen 44; CT44; Transmembrane phosphatase with tensin homology; Tumor antigen BJ-HCC-5
UniProt Gene Name
TPTE
UniProt Synonym Gene Names
CT44
UniProt Entry Name
TPTE_HUMAN
NCBI Protein Information
putative tyrosine-protein phosphatase TPTE; tumor antigen BJ-HCC-5; cancer/testis antigen 44; PTEN-related tyrosine phosphatase; tensin, putative protein-tyrosine phosphatase

NCBI Summary for TPTE

This gene encodes a PTEN-related tyrosine phosphatase which may play a role in the signal transduction pathways of the endocrine or spermatogenic function of the testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

UniProt Comments for TPTE

TPTE: Could be involved in signal transduction. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cancer Testis Antigen (CTA); Membrane protein, multi-pass; Receptor protein phosphatase, tyrosine; Membrane protein, integral; EC 3.1.3.48; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 21p11

Cellular Component: integral to membrane

Molecular Function: protein tyrosine/serine/threonine phosphatase activity; ion channel activity; protein tyrosine phosphatase activity

Biological Process: signal transduction; protein amino acid dephosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TPTE antibody

 Reference Product  PubMed Publications
 NEK3 antibody  >1 publications with TPTE and NEK3

Organs/Tissues associated with anti-TPTE antibody

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