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SLC39A14 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244834

MBS244834 is an antibody targeting SLC39A14. Also known as Rabbit Polyclonal to Human SLC39A14 / ZIP14. Reactive in Gibbon, Gorilla, Human, Monkey, Orangutan, PigPredicted Reactivity: Bovine, Dog, Hamster (at least 90% immunogen sequence identity). Host:… More details

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Product Overview

Online Datasheet in PDF
Product Name
SLC39A14 / ZIP14, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human SLC39A14 / ZIP14
Product Gene Name
Product Synonym Gene Name
ZIP14
Product Synonym Names
Anti-SLC39A14 / ZIP14 Antibody (Cytoplasmic Domain) IHC-plus; SLC39A14; KIAA0062; LZT-Hs4; NET34; Zrt-; Irt-like protein 14; Zinc transporter ZIP14; ZIP-14; ZIP14; Zrt- and Irt-like protein 14; Cig19; Human SLC39A14; ZIP14
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human, Monkey, Orangutan, Pig
Predicted Reactivity: Bovine, Dog, Hamster (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human SLC39A14. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
54,057 Da
OMIM
608736
3D Structure
ModBase 3D Structure for Q15043
Target Species
Human
Immunogen Description
Synthetic 15 amino acid peptide from cytoplasmic domain of human SLC39A14. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Pig (100%); Bovine, Dog, Hamster, Elephant, Panda (93%); Rat, Bat.
Immunogen Type
Synthetic peptide
Immunogen
SLC39A14 / ZIP14 antibody was raised against synthetic 15 amino acid peptide from cytoplasmic domain of human SLC39A14. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Pig (100%); Bovine, Dog, Hamster, Elephant, Panda (93%); Rat, Bat, Rabbit, Horse, Opossum (87%); Mouse (80%).
Antigen Modification
Cytoplasmic Domain
Applications Tested/Suitable for anti-SLC39A14 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-SLC39A14 antibody
IHC-P (5 - 7.5 ug/ml)

Immunohistochemistry (IHC) of anti-SLC39A14 antibody

Anti-SLC39A14 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-SLC39A14 Polyclonal Antibody – Cat# MBS244834

Immunohistochemistry (IHC) of anti-SLC39A14 antibody

Anti-SLC39A14 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-SLC39A14 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244834

Other Notes

Small volumes of anti-SLC39A14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC39A14. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc transporter ZIP14 isoform a
NCBI Official Synonym Full Names
solute carrier family 39 (zinc transporter), member 14
NCBI Official Symbol
SLC39A14
NCBI Official Synonym Symbols
NET34; ZIP14; cig19; LZT-Hs4
UniProt Protein Name
Zinc transporter ZIP14
UniProt Synonym Protein Names
LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; Solute carrier family 39 member 14; Zrt- and Irt-like protein 14; ZIP-14
Protein Family
UniProt Gene Name
SLC39A14
UniProt Synonym Gene Names
KIAA0062; ZIP14; LZT-Hs4; ZIP-14
UniProt Entry Name
S39AE_HUMAN
NCBI Protein Information
zinc transporter ZIP14; ZIP-14; Zrt-, Irt-like protein 14; zrt- and Irt-like protein 14; solute carrier family 39 member 14; LIV-1 subfamily of ZIP zinc transporter 4; solute carrier family 39 (metal ion transporter), member 14

NCBI Summary for SLC39A14

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
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UniProt Comments for SLC39A14

SLC39A14: May mediate cellular uptake of nontransferrin-bound iron. Broad-scope metal ion transporter with a preference for zinc uptake. Belongs to the ZIP transporter (TC 2.A.5) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, SLC family; Membrane protein, integral; Transporter; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: Golgi apparatus; lamellipodium; integral to plasma membrane; endoplasmic reticulum; integral to membrane; plasma membrane

Molecular Function: zinc ion transmembrane transporter activity; ferrous iron transmembrane transporter activity

Biological Process: ferrous iron transport; cellular zinc ion homeostasis; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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