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PGRMC2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS245783

MBS245783 is an antibody targeting PGRMC2. Also known as Mouse Monoclonal [clone 3C11] (IgG1,k) to Human PGRMC2. Reactive in Human, Mouse, Rat. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PGRMC2, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 3C11] (IgG1,k) to Human PGRMC2
Product Gene Name
Product Synonym Names
Anti-PGRMC2 Antibody (clone 3C11) IHC-plus; PGRMC2; PMBP; Steroid receptor protein DG6; DG6; Human PGRMC2
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
3C11
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, pH 7.4. Sourced in Ascites.
Purity/Purification
Protein A Purified
Concentration
0.45 mg/ml (lot specific)
Specificity
Human PGRMC2
Preparation and Storage
Store at -20 degree C or lower. Aliquot to avoid repeated freezing and thawing.
Molecular Weight
26,170 Da
OMIM
607735
Target Species
Human
Immunogen Description
PGRMC2 (NP_006311, 124 a.a. ~ 224 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen
PGRMC2 antibody was raised against pGRMC2 (NP_006311, 124 a.a. ~ 224 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications Tested/Suitable for anti-PGRMC2 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-PGRMC2 antibody
ELISA, IHC-P (1 - 10 ug/ml), WB (1:500 - 1:1000)
Usage: Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot using cell line lysates and the recombinant protein used as the immunogen.

Immunohistochemistry (IHC) of anti-PGRMC2 antibody

Anti-PGRMC2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 1 ug/ml.
Mouse Anti-PGRMC2 Monoclonal Antibody – Cat# MBS245783

Western Blot (WB) of anti-PGRMC2 antibody

Antibody, Western blot of PGRMC2 expression in HeLa.
Mouse Anti-PGRMC2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS245783

Western Blot (WB) of anti-PGRMC2 antibody

Antibody, Western blot of PGRMC2 expression in NIH/3T3.
Mouse Anti-PGRMC2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS245783

Western Blot (WB) of anti-PGRMC2 antibody

Antibody, Western blot of PGRMC2 expression in PC-12.
Mouse Anti-PGRMC2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS245783

ELISA (EIA) of anti-PGRMC2 antibody

Detection limit for recombinant GST tagged PGRMC2 is approximately 0.3 ng/ml as a capture antibody.
Mouse Anti-PGRMC2 Monoclonal Antibody, ELISA (EIA) – Cat# MBS245783

Other Notes

Small volumes of anti-PGRMC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PGRMC2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens chromosome 4, GRCh37.p13 Primary Assembly
NCBI Official Synonym Full Names
progesterone receptor membrane component 2
NCBI Official Symbol
PGRMC2
NCBI Official Synonym Symbols
DG6; PMBP
UniProt Protein Name
Membrane-associated progesterone receptor component 2
UniProt Synonym Protein Names
Progesterone membrane-binding protein; Steroid receptor protein DG6
UniProt Gene Name
PGRMC2
UniProt Synonym Gene Names
DG6; PMBP
UniProt Entry Name
PGRC2_HUMAN
NCBI Protein Information
membrane-associated progesterone receptor component 2; steroid receptor protein DG6; progesterone membrane binding protein

UniProt Comments for PGRMC2

PGRMC2: Receptor for steroids (Potential). Belongs to the cytochrome b5 family. MAPR subfamily.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 4q26

Cellular Component: membrane; integral to membrane; endomembrane system

Molecular Function: heme binding; steroid hormone receptor activity; steroid binding

Biological Process: steroid hormone mediated signaling
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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