Human C6 cDNA Clone Expression Plasmid – Cat# MBS1267367

C6 cDNA Clone – Complement Component 6 (Human)

Name: C6 cDNA Clone; Complement Component 6; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1267367
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1267367

MBS1267367 is a cDNA clone targeting C6. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

C6, cDNA Clone

Full Product Name

C6 cDNA Clone

Product Gene Name

C6 cdna clone

Sequence

atggccagac gctctgtctt gtacttcatc ctgctgaatg ctctgatcaa caagggccaa gcctgcttct gtgatcacta tgcatggact cagtggacca gctgctcaaa aacttgcaat tctggaaccc agagcagaca cagacaaata gtagtagata agtactacca ggaaaacttt tgtgaacaga tttgcagcaa gcaggagact agagaatgta actggcaaag atgccccatc aactgcctcc tgggagattt tggaccatgg tcagactgtg acccttgtat tgaaaaacag tctaaagtta gatctgtctt gcgtcccagt cagtttgggg gacagccatg cactgagcct ctggtagcct ttcaaccatg cattccatct aagctctgca aaattgaaga ggctgactgc aagaataaat ttcgctgtga cagtggccgc tgcattgcca gaaagttaga atgcaatgga gaaaatgact gtggagacaa ttcagatgaa agggactgtg ggaggacaaa ggcagtatgc acacggaagt ataatcccat ccctagtgta cagttgatgg gcaatgggtt tcattttctg gcaggagagc ccagaggaga agtccttgat aactctttca ctggaggaat atgtaaaact gtcaaaagca gtaggacaag taatccatac cgtgttccgg ccaatctgga aaatgtcggc tttgaggtac aaactgcaga agatgacttg aaaacagatt tctacaagga tttaacttct cttggacaca atgaaaatca acaaggctca ttctcaagtc agggggggag ctctttcagt gtaccaattt tttattcctc aaagagaagt gaaaatatca accataattc tgccttcaaa caagccattc aagcctctca caaaaaggat tctagtttta ttaggatcca taaagtgatg aaagtcttaa acttcacaac gaaagctaaa gatctgcacc tttctgatgt ctttttgaaa gcacttaacc atctgcctct agaatacaac tctgctttgt acagccgaat attcgatgac tttgggactc attacttcac ctctggctcc ctgggaggcg tgtatgacct tctctatcag tttagcagtg aggaactaaa gaactcaggt ttaaccgagg aagaagccaa acactgtgtc aggattgaaa caaagaaacg cgttttattt gctaagaaaa caaaagtgga acataggtgc accaccaaca agctgtcaga gaaacatgaa ggttcattta tacagggagc agagaaatcc atatccctga ttcgaggtgg aaggagtgaa tatggagcag ctttggcatg ggagaaaggg agctctggtc tggaggagaa gacattttct gagtggttag aatcagtgaa ggaaaatcct gctgtgattg actttgagct tgcccccatc gtggacttgg taagaaacat cccctgtgca gtgacaaaac ggaacaacct caggaaagct ttgcaagagt atgcagccaa gttcgatcct tgccagtgtg ctccatgccc taataatggc cgacccaccc tctcagggac tgaatgtctg tgtgtgtgtc agagtggcac ctatggtgag aactgtgaga aacagtctcc agattataaa tccaatgcag tagacggaca gtggggttgt tggtcttcct ggagtacctg tgatgctact tataagagat cgagaacccg agaatgcaat aatcctgccc cccaacgagg agggaaacgc tgtgaggggg agaagcgaca agaggaagac tgcacatttt caatcatgga aaacaatgga caaccatgta tcaatgatga tgaagaaatg aaagaggtcg atcttcctga gatagaagca gattccgggt gtcctcagcc agttcctcca gaaaatggat ttatccggaa tgaaaagcaa ctatacttgg ttggagaaga tgttgaaatt tcatgcctta ctggctttga aactgttgga taccagtact tcagatgctt accagacggg acctggagac aaggggatgt ggaatgccaa cggacggagt gcatcaagcc agttgtgcag gaagtcctga caattacacc atttcagaga ttgtatagaa ttggtgaatc cattgagcta acttgcccca aaggctttgt tgttgctggg ccatcaaggt acacatgcca ggggaattcc tggacaccac ccatttcaaa ctctctcacc tgtgaaaaag atactctaac aaaattaaaa ggccattgtc agctgggaca gaaacaatca ggatctgaat gcatttgtat gtctccagaa gaagactgta gccatcattc agaagatctc tgtgtgtttg acacagactc caacgattac tttacttcac ccgcttgtaa gtttttggct gagaaatgtt taaataatca gcaactccat tttctacata ttggttcctg ccaagacggc cgccagttag aatggggtct tgaaaggaca agactttcat ccaacagcac aaagaaagaa tcctgtggct atgacacctg ctatgactgg gaaaaatgtt cagcctccac ttccaaatgt gtctgcctat tgcccccaca gtgcttcaag ggtggaaacc aactctactg tgtcaaaatg ggatcatcaa caagtgagaa aacattgaac atctgtgaag tgggaactat aagatgtgca aacaggaaga tggaaatact gcatcctgga aagtgtttgg cctag

Molecular Weight

104,786 Da

OMIM

217050

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of C6 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for C6. It may not necessarily be applicable to this product.

NCBI GI #

23273481

NCBI GeneID

729

NCBI Accession #

BC035723

UniProt Related Accession #

P13671

NCBI Official Full Name

Homo sapiens complement component 6, mRNA

NCBI Official Synonym Full Names

complement C6

NCBI Official Symbol

UniProt Protein Name

Complement component C6

Protein Family

Complement component

UniProt Gene Name

UniProt Entry Name

CO6_HUMAN

NCBI Protein Information

complement component C6

NCBI Summary for C6

This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]

UniProt Comments for C6

C6: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. Defects in C6 are the cause of complement component 6 deficiency (C6D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5p13

Cellular Component: extracellular region

Molecular Function: protein binding

Biological Process: complement activation; regulation of complement activation

Disease: Complement Component 6 Deficiency

Research Articles on C6

1. Complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with C6 cdna clone

Products by Pathway	Pathway Diagram
Complement Activation, Classical Pathway antibodies	Complement Activation, Classical Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement Cascade Pathway antibodies	Complement Cascade Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Prion Diseases Pathway antibodies	Prion Diseases Pathway Diagram
Prion Diseases Pathway antibodies	Prion Diseases Pathway Diagram
Systemic Lupus Erythematosus Pathway antibodies	Systemic Lupus Erythematosus Pathway Diagram

Diseases associated with C6 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>3922 publications with C6 and Neoplasms
Nervous System Diseases Antibodies	>2944 publications with C6 and Nervous System Diseases
Brain Diseases Antibodies	>1434 publications with C6 and Brain Diseases
Necrosis Antibodies	>372 publications with C6 and Necrosis
Complement Component 6 Deficiency Antibodies	>301 publications with C6 and Complement Component 6 Deficiency
Immune System Diseases Antibodies	>290 publications with C6 and Immune System Diseases
Inflammation Antibodies	>257 publications with C6 and Inflammation
Edema Antibodies	>155 publications with C6 and Edema
Congenital Abnormalities Antibodies	>133 publications with C6 and Congenital Abnormalities
Kidney Diseases Antibodies	>131 publications with C6 and Kidney Diseases

Organs/Tissues associated with C6 cdna clone

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>473 publications with C6 and Liver
Kidney Antibodies	>371 publications with C6 and Kidney
Heart Antibodies	>299 publications with C6 and Heart
Lung Antibodies	>241 publications with C6 and Lung
Connective Tissue Antibodies	>85 publications with C6 and Connective Tissue
Bladder Antibodies	>73 publications with C6 and Bladder
Pancreas Antibodies	>36 publications with C6 and Pancreas
Testis Antibodies	>35 publications with C6 and Testis
Uterus Antibodies	>15 publications with C6 and Uterus