C-Type Natriuretic (CNP) ELISA Kit for Rabbit

Name: Rabbit CNP ELISA Kit; C-Type Natriuretic; MyBioSource
Brand: MyBioSource
SKU: MBS024661
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS024661

MBS024661 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the C-Type Natriuretic Peptide (CNP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

C-Type Natriuretic Peptide (CNP), ELISA Kit

Full Product Name

Rabbit C-Type Natriuretic Peptide ELISA Kit

Product Gene Name

CNP elisa kit

Species Reactivity

Rabbit

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

13,246 Da

Chromosome Location

Chromosome: 2; NC_000002.11 (232786805..232791038, complement). Location: 2q24-qter

OMIM

600296

3D Structure

ModBase 3D Structure for P23582

Other Notes

Small volumes of CNP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CNP. It may not necessarily be applicable to this product.

NCBI GI #

13249346

NCBI GeneID

4880

NCBI Accession #

NP_077720.1

UniProt Primary Accession #

P23582

UniProt Secondary Accession #

Q4ZG41

UniProt Related Accession #

P23582

GenBank Nucleotide #

NM_024409.2

NCBI Official Full Name

C-type natriuretic peptide

NCBI Official Synonym Full Names

natriuretic peptide C

NCBI Official Symbol

NPPC

NCBI Official Synonym Symbols

CNP; CNP2

UniProt Protein Name

C-type natriuretic peptide

Protein Family

2',3'-cyclic-nucleotide 3'-phosphodiesterase

UniProt Gene Name

NPPC

UniProt Synonym Gene Names

CNP2

UniProt Entry Name

ANFC_HUMAN

NCBI Protein Information

C-type natriuretic peptide; natriuretic peptide precursor C

NCBI Summary for CNP

The protein encoded by this gene is proteolytically processed to form a secreted hormone of the natriuretic peptide family. The encoded hormone regulates the growth and differentiation of cartilaginous growth plate chondrocytes and may also be vasoactive and natriuretic. [provided by RefSeq, Sep 2011]

UniProt Comments for CNP

NPPC: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3. Belongs to the natriuretic peptide family.

Protein type: Secreted, signal peptide; Secreted; Hormone

Chromosomal Location of Human Ortholog: 2q37.1

Cellular Component: extracellular space; secretory granule

Molecular Function: protein homodimerization activity; peptide hormone receptor binding; hormone activity; receptor binding

Biological Process: response to drug; cGMP biosynthetic process; ossification; regulation of smooth muscle cell proliferation; regulation of cAMP metabolic process; regulation of multicellular organism growth; negative regulation of meiotic cell cycle; positive regulation of vasodilation; negative regulation of DNA metabolic process; post-embryonic development; positive regulation of osteoblast differentiation; negative regulation of cell proliferation; response to ethanol; positive regulation of cGMP biosynthetic process; receptor guanylyl cyclase signaling pathway; response to hypoxia; regulation of cGMP metabolic process; regulation of blood vessel size

Research Articles on CNP

1. CNP synthesis (as measured by NTproCNP levels in plasma) is closely related to linear growth in healthy children at all ages. We propose NTproCNP as a biomarker of linear growth.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CNP elisa kit

Reference Product	PubMed Publications
NPR2 elisa kit	>14 publications with CNP and NPR2
NPPA elisa kit	>6 publications with CNP and NPPA
NPR3 elisa kit	>5 publications with CNP and NPR3
NPPB elisa kit	>4 publications with CNP and NPPB
NPR1 elisa kit	>3 publications with CNP and NPR1

Diseases associated with CNP elisa kit

Disease Name	Pubmed Publications
Bone Diseases, Developmental Antibodies	>6 publications with CNP and Bone Diseases, Developmental
Nervous System Diseases Antibodies	>5 publications with CNP and Nervous System Diseases
Growth Disorders Antibodies	>3 publications with CNP and Growth Disorders
Heart Diseases Antibodies	>2 publications with CNP and Heart Diseases
Cardiovascular Diseases Antibodies	>2 publications with CNP and Cardiovascular Diseases
Disease Models, Animal Antibodies	>2 publications with CNP and Disease Models, Animal
Hypertrophy Antibodies	>2 publications with CNP and Hypertrophy
Cartilage Diseases Antibodies	>2 publications with CNP and Cartilage Diseases
Hypertension Antibodies	>1 publications with CNP and Hypertension
Kidney Diseases Antibodies	>1 publications with CNP and Kidney Diseases

Organs/Tissues associated with CNP elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>11 publications with CNP and Brain