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BOB Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246981

G protein-coupled receptor GPR15 is an Orphan-A GPCR with an unknown ligand. Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major… More details

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Product Overview

Online Datasheet in PDF
Product Name
BOB / GPR15, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human BOB / GPR15
Product Gene Name
Product Synonym Gene Name
GPR15
Product Synonym Names
Anti-BOB / GPR15 Antibody (Cytoplasmic Domain) IHC-plus; GPR15; Brother of Bonzo; G protein-coupled receptor 15; G-protein coupled receptor 15; BOB; Gpr-15; Human BOB; GPR15
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Chimpanzee, Gorilla, Human, Monkey
Predicted Reactivity: Rabbit (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GPR15. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
40,787 Da
OMIM
601166
3D Structure
ModBase 3D Structure for P49685
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human GPR15. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (100%); Elephant, Rabbit (94%); Bovine, Hamster, Panda.
Immunogen Type
Synthetic peptide
Immunogen
BOB / GPR15 antibody was raised against synthetic 16 amino acid peptide from 1st cytoplasmic domain of human GPR15. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (100%); Elephant, Rabbit (94%); Bovine, Hamster, Panda, Horse (88%); Mouse, Dog, Bat, Pig (81%).
Antigen Modification
Cytoplasmic Domain

Product Categories/Family for anti-BOB antibody

Applications Tested/Suitable for anti-BOB antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-BOB antibody
IHC-P (10 - 20 ug/ml)

Immunohistochemistry (IHC) of anti-BOB antibody

Anti-BOB / GPR15 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-BOB Polyclonal Antibody – Cat# MBS246981

Immunohistochemistry (IHC) of anti-BOB antibody

Anti-BOB / GPR15 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-BOB Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS246981

Immunohistochemistry (IHC) of anti-BOB antibody

Anti-BOB / GPR15 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-BOB Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS246981

Immunohistochemistry (IHC) of anti-BOB antibody

Anti-GPR15 antibody IHC of human colon, surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-BOB Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS246981

Other Notes

Small volumes of anti-BOB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BOB purchase

MBS246981 is an antibody targeting BOB. Also known as Rabbit Polyclonal to Human BOB / GPR15. Reactive in Gibbon, Chimpanzee, Gorilla, Human, Monkey
Predicted Reactivity: Rabbit (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BOB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G-protein coupled receptor 15
NCBI Official Synonym Full Names
G protein-coupled receptor 15
NCBI Official Symbol
GPR15
NCBI Official Synonym Symbols
BOB
UniProt Protein Name
G-protein coupled receptor 15
UniProt Synonym Protein Names
Brother of Bonzo; BoB
UniProt Gene Name
GPR15
UniProt Synonym Gene Names
BoB
UniProt Entry Name
GPR15_HUMAN
NCBI Protein Information
G-protein coupled receptor 15; brother of Bonzo

NCBI Summary for BOB

This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012]

UniProt Comments for BOB

GPR15: Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3q11.2-q13.1

Cellular Component: integral to plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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