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TGM7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248255

MBS248255 is an antibody targeting TGM7. Also known as Rabbit Polyclonal to Human TGM7 / Transglutaminase 7. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TGM7 / Transglutaminase 7, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human TGM7 / Transglutaminase 7
Product Gene Name
Product Synonym Names
Anti-TGM7 / Transglutaminase 7 Antibody (Internal) IHC-plus; TGM7; TG(Z); TGase Z; TGase-7; Transglutaminase Z; TGMZ; TGZ; Transglutaminase-7; Transglutaminase 7; Human TGM7; Transglutaminase 7
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human TGM7 / Transglutaminase 7. TGM7 antibody is predicted to not cross-react with other TGase protein family members. At least two isoforms of TGM7 are known to exist; this antibody will recognize both isoforms.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
79,941 Da
OMIM
606776
3D Structure
ModBase 3D Structure for Q96PF1
Target Species
Human
Immunogen Description
A 13 amino acid peptide near the center of human TGM7
Immunogen Type
Synthetic peptide
Antigen Modification
Internal
Applications Tested/Suitable for anti-TGM7 antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-TGM7 antibody
ELISA, ICC (2.5 ug/ml), IF (10 ug/ml), IHC-P (5 ug/ml), WB (1 ug/ml)

Immunohistochemistry (IHC) of anti-TGM7 antibody

Anti-TGM7 / Transglutaminase 7 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-TGM7 Polyclonal Antibody – Cat# MBS248255

Immunofluorescence (IF) of anti-TGM7 antibody

Immunofluorescence of TGM7 in A549 cells with TGM7 antibody at 10 µg/mL.
Rabbit Anti-TGM7 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS248255

Immunocytochemistry (ICC) of anti-TGM7 antibody

Immunocytochemistry of TGM7 in A549 cells with TGM7 antibody at 2.5 µg/mL.
Rabbit Anti-TGM7 Polyclonal Antibody, Immunocytochemistry (ICC) – Cat# MBS248255

Western Blot (WB) of anti-TGM7 antibody

Western blot analysis of TGM7 in human lung tissue lysate with TGM7 antibody at 1 ug/ml.
Rabbit Anti-TGM7 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248255

Other Notes

Small volumes of anti-TGM7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TGM7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein-glutamine gamma-glutamyltransferase Z
NCBI Official Synonym Full Names
transglutaminase 7
NCBI Official Symbol
TGM7
NCBI Official Synonym Symbols
TGMZ
UniProt Protein Name
Protein-glutamine gamma-glutamyltransferase Z
UniProt Synonym Protein Names
Transglutaminase Z (EC:2.3.2.13); TG(Z); TGZ; TGase Z; Transglutaminase-7; TGase-7
UniProt Gene Name
TGM7
UniProt Synonym Gene Names
TG(Z); TGZ; TGase Z; TGase-7
UniProt Entry Name
TGM7_HUMAN
NCBI Protein Information
protein-glutamine gamma-glutamyltransferase Z; TGZ; TGase Z; TGase-7; transglutaminase Z; transglutaminase-7

NCBI Summary for TGM7

Transglutaminases (TGM; EC 2.3.2.13) are a family of structurally and functionally related enzymes that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. For additional background information on transglutaminases, see TGM1 (MIM 190195).[supplied by OMIM, Jul 2002]
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UniProt Comments for TGM7

TGM7: an enzyme of the transglutaminase family that catalyzes the crosslinking of proteins and the conjugation of polyamines to proteins. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent.

Protein type: Transferase; EC 2.3.2.13

Chromosomal Location of Human Ortholog: 15q15.2

Molecular Function: protein-glutamine gamma-glutamyltransferase activity; metal ion binding

Biological Process: peptide cross-linking
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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