Goat Anti-PIM2 Polyclonal Antibody – Cat# MBS248267

Human, Heart: Formalin-Fixed Paraffin-Embedded (FFPE)

PIM2 Antibody – Goat Polyclonal

Name: PIM2 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS248267
Price: 625 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248267

PIM-2, a PIM protein kinase, is involved in progression of T-cell lymphoma. Two transcripts of this gene have been identified. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

PIM2 / Pim-2, Polyclonal Antibody

Full Product Name

Goat Polyclonal to Human PIM2 / Pim-2

Product Gene Name

anti-PIM2 antibody

Product Synonym Gene Name

Pim-2

Product Synonym Names

Anti-PIM2 / Pim-2 Antibody (aa23-36) IHC-plus; PIM2; DXCch3; Pim-2 oncogene; Pim-2h; Tic-1; Proviral integration site 2; Human PIM2; Pim-2

Clonality

Polyclonal

Host

Goat

Species Reactivity

Human

Form/Format

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide

Purity/Purification

Immunoaffinity Purified

Concentration

0.5 mg/ml (lot specific)

Specificity

Human PIM2 / Pim-2

Preparation and Storage

Store at -20 degree C. Minimize freezing and thawing.

Molecular Weight

34,190 Da

OMIM

300295

3D Structure

ModBase 3D Structure for Q9P1W9

Target Species

Human

Immunogen Description

Synthetic peptide C-KDREAFEAEYRLGP from an internal region (near N-terminus) of human PIM2 / Pim-2 (NP_006866.2). Percent identity by BLAST analysis: Hamster (86%).

Immunogen Type

Synthetic peptide

Immunogen

PIM2 / Pim-2 antibody was raised against synthetic peptide C-KDREAFEAEYRLGP from an internal region (near N-terminus) of human PIM2 / Pim-2 (NP_006866.2). Percent identity by BLAST analysis: Hamster (86%).

Antigen Modification

aa23-36

Product Categories/Family for anti-PIM2 antibody

Family: Protein Kinase; Subfamily: PIM

Applications Tested/Suitable for anti-PIM2 antibody

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)

Application Notes for anti-PIM2 antibody

ELISA (1:64000), IHC-P (5 ug/ml), WB (0.5 - 1 ug/ml)
Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: In transfected HEK293 transiently expressing Human PIM2 (myc and DYKDDDDK tagged), a band of approx. 38kD is observed. No bands are observed in mock-transfected HEK293 and the sa...

Other Notes

Small volumes of anti-PIM2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PIM2 purchase

MBS248267 is an antibody targeting PIM2. Also known as Goat Polyclonal to Human PIM2 / Pim-2. Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for PIM2. It may not necessarily be applicable to this product.

NCBI GI #

42821112

NCBI GeneID

11040

NCBI Accession #

NP_006866.2

UniProt Primary Accession #

Q9P1W9

UniProt Secondary Accession #

Q99739; A8K4G6

UniProt Related Accession #

Q9P1W9

GenBank Nucleotide #

NM_006875.3

NCBI Official Full Name

serine/threonine-protein kinase pim-2

NCBI Official Synonym Full Names

Pim-2 proto-oncogene, serine/threonine kinase

NCBI Official Symbol

PIM2

UniProt Protein Name

Serine/threonine-protein kinase pim-2

UniProt Synonym Protein Names

Pim-2h

Protein Family

Serine/threonine-protein kinase

UniProt Gene Name

PIM2

UniProt Entry Name

PIM2_HUMAN

NCBI Protein Information

serine/threonine-protein kinase pim-2; pim-2h; pim-2 oncogene; serine/threonine protein kinase pim-2; proto-oncogene Pim-2 (serine threonine kinase)

NCBI Summary for PIM2

This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.[provided by RefSeq, Nov 2009]

UniProt Comments for PIM2

Pim2: a Ca(2 )/calmodulin-dependent protein kinase of the PIM family. Highly expressed in hematopoietic tissues, in leukemic and lymphoma cell lines, testis, small intestine, colon and colorectal adenocarcinoma cells.

Protein type: Protein kinase, CAMK; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Oncoprotein; CAMK group; PIM family

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: cytoplasm

Molecular Function: protein serine/threonine kinase activity; ATP binding

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; protein stabilization; response to virus; protein amino acid autophosphorylation; positive regulation of transcription, DNA-dependent; regulation of mitotic cell cycle; male meiosis; protein amino acid phosphorylation; cell proliferation; negative regulation of cell proliferation; apoptotic mitochondrial changes; positive regulation of autophagy; G1/S transition of mitotic cell cycle; negative regulation of apoptosis

Research Articles on PIM2

1. Blocking the activities of PIM kinases(PIM1, PIM2 and PIM3) could prevent pancreatic cancer development. PIM kinases(PIM1, PIM2 and PIM3) may be a novel target for cancer therapy

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PIM2 antibody

Reference Product	PubMed Publications
BAD antibody	>14 publications with PIM2 and BAD
FOXP3 antibody	>3 publications with PIM2 and FOXP3
SOCS3 antibody	>1 publications with PIM2 and SOCS3
IL3 antibody	>1 publications with PIM2 and IL3
API5 antibody	>1 publications with PIM2 and API5
TNFSF13B antibody	>1 publications with PIM2 and TNFSF13B

Pathways associated with anti-PIM2 antibody

Products by Pathway	Pathway Diagram
Acute Myeloid Leukemia Pathway antibodies	Acute Myeloid Leukemia Pathway Diagram
Acute Myeloid Leukemia Pathway antibodies	Acute Myeloid Leukemia Pathway Diagram

Diseases associated with anti-PIM2 antibody

Disease Name	Pubmed Publications
Liver Diseases Antibodies	>13 publications with PIM2 and Liver Diseases
Inflammation Antibodies	>12 publications with PIM2 and Inflammation
Leukemia, Myeloid, Acute Antibodies	>9 publications with PIM2 and Leukemia, Myeloid, Acute
Necrosis Antibodies	>8 publications with PIM2 and Necrosis
Disease Models, Animal Antibodies	>7 publications with PIM2 and Disease Models, Animal
Liver Neoplasms Antibodies	>6 publications with PIM2 and Liver Neoplasms
Carcinoma, Hepatocellular Antibodies	>4 publications with PIM2 and Carcinoma, Hepatocellular
Adenocarcinoma Antibodies	>4 publications with PIM2 and Adenocarcinoma
Metaplasia Antibodies	>3 publications with PIM2 and Metaplasia
Lung Neoplasms Antibodies	>2 publications with PIM2 and Lung Neoplasms

Organs/Tissues associated with anti-PIM2 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>59 publications with PIM2 and Blood
Bone Antibodies	>20 publications with PIM2 and Bone
Bone Marrow Antibodies	>15 publications with PIM2 and Bone Marrow
Liver Antibodies	>11 publications with PIM2 and Liver
Prostate Antibodies	>10 publications with PIM2 and Prostate
Thymus Antibodies	>6 publications with PIM2 and Thymus
Lung Antibodies	>6 publications with PIM2 and Lung
Lymph Node Antibodies	>4 publications with PIM2 and Lymph Node
Spleen Antibodies	>4 publications with PIM2 and Spleen
Lymph Antibodies	>3 publications with PIM2 and Lymph