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DENR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248609

Density-regulated protein (DRP) is expressed at high cell density but not during growth arrest. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
DENR / Density Regulated, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human DENR / Density Regulated
Product Gene Name
Product Synonym Names
Anti-DENR / Density Regulated Antibody (aa148-198) IHC-plus; DENR; Density-regulated protein; DRP1; Protein DRP1; DRP; SMAP-3; Human DENR; Density Regulated
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Bovine, Chicken, Xenopus, Goat, Human, Mouse, Rat
Form/Format
Tris-citrate/phosphate buffer, pH 7-8, 0.09% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Region between residue 148 and 198 of human Density-Regulated Protein using the numbering given in entry NP_003668.2 (GeneID 8562).
Preparation and Storage
Store at 2-8 degree C for up to 1 year.
Molecular Weight
22,092 Da
OMIM
604550
3D Structure
ModBase 3D Structure for O43583
Usage Not Recommended
Immunoprecipitation (IP)
Target Species
Human
Antigen Modification
aa148-198
Applications Tested/Suitable for anti-DENR antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-DENR antibody
IHC-P (5 ug/ml), WB (1:2000 - 1:10000)

Immunohistochemistry (IHC) of anti-DENR antibody

Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-DENR Polyclonal Antibody – Cat# MBS248609

Other Notes

Small volumes of anti-DENR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DENR purchase

MBS248609 is an antibody targeting DENR. Also known as Rabbit Polyclonal (IgG) to Human DENR / Density Regulated. Reactive in Bovine, Chicken, Xenopus, Goat, Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DENR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
density-regulated protein
NCBI Official Synonym Full Names
density-regulated protein
NCBI Official Symbol
DENR
NCBI Official Synonym Symbols
DRP; DRP1; SMAP-3
UniProt Protein Name
Density-regulated protein
UniProt Synonym Protein Names
Protein DRP1; Smooth muscle cell-associated protein 3; SMAP-3
UniProt Gene Name
DENR
UniProt Synonym Gene Names
DRP1; DRP; SMAP-3
UniProt Entry Name
DENR_HUMAN
NCBI Protein Information
density-regulated protein; smooth muscle cell associated protein-3; smooth muscle cell-associated protein 3

NCBI Summary for DENR

This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. [provided by RefSeq, Jul 2008]
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UniProt Comments for DENR

DENR: May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Plays a role in the modulation of the translational profile of a subset of cancer- related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1. Belongs to the DENR family.

Protein type: RNA-binding; Translation

Chromosomal Location of Human Ortholog: 12q24.31

Molecular Function: protein binding; translation initiation factor activity

Biological Process: ribosome disassembly; formation of translation preinitiation complex
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DENR antibody

 Reference Product  PubMed Publications
 MCTS1 antibody  >4 publications with DENR and MCTS1

Diseases associated with anti-DENR antibody

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