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TAC3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS248745

MBS248745 is an antibody targeting TAC3. Also known as Rabbit Polyclonal to Human TAC3 / Tachykinin. Reactive in Human. Host: Rabbit. More details

$650 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TAC3 / Tachykinin, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human TAC3 / Tachykinin
Product Gene Name
Product Synonym Names
Anti-TAC3 / Tachykinin Antibody (aa53-83) IHC-plus; TAC3; Gamma tachykinin 3; Neuromedin K; Neurokinin beta; NKB; NKNB; Neurokinin B; ZNEUROK1; Tachykinin 3; Tachykinin-3; HH10; Preprotachykinin B; PRO1155; Tachykinin; Human TAC3; Tachykinin
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.09% sodium azide
Purity/Purification
Immunoaffinity Purified
Specificity
Human Tachykinin
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Molecular Weight
11,358 Da
OMIM
gene 614839
3D Structure
ModBase 3D Structure for Q9UHF0
Target Species
Human
Immunogen Description
KLH-conjugated synthetic peptide from internal region of human TAC3.
Immunogen Type
Synthetic peptide
Immunogen
TAC3 / Tachykinin antibody was raised against kLH-conjugated synthetic peptide from internal region of human TAC3.
Antigen Modification
aa53-83
Applications Tested/Suitable for anti-TAC3 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-TAC3 antibody
IHC-P (1:10 - 1:75), WB (1:1000)

Immunohistochemistry (IHC) of anti-TAC3 antibody

Anti-TAC3 / Tachykinin antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-TAC3 Polyclonal Antibody – Cat# MBS248745

Immunohistochemistry (IHC) of anti-TAC3 antibody

Anti-TAC3 / Tachykinin antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-TAC3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS248745

Western Blot (WB) of anti-TAC3 antibody

TAC3 Antibody (Center) Western blot of Jurkat cell line lysates (35 ug/lane). This demonstrates the TAC3 antibody detected the TAC3 protein (arrow).
Rabbit Anti-TAC3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS248745

Other Notes

Small volumes of anti-TAC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TAC3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tachykinin-3 isoform 1 preproprotein
NCBI Official Synonym Full Names
tachykinin 3
NCBI Official Symbol
TAC3
NCBI Official Synonym Symbols
NKB; HH10; NKNB; PRO1155; ZNEUROK1
UniProt Protein Name
Tachykinin-3
UniProt Synonym Protein Names
ZNEUROK1Neurokinin-B; NKBAlternative name(s):Neuromedin-K
Protein Family
UniProt Gene Name
TAC3
UniProt Synonym Gene Names
NKNB; NKB
UniProt Entry Name
TKNK_HUMAN
NCBI Protein Information
tachykinin-3; neurokinin b; neuromedin K; gamma tachykinin 3; preprotachykinin B; preprotachykinin-B

NCBI Summary for TAC3

This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
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UniProt Comments for TAC3

TAC3: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; receptor binding

Biological Process: tachykinin signaling pathway; neuropeptide signaling pathway; female pregnancy

Disease: Hypogonadotropic Hypogonadism 10 With Or Without Anosmia
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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