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TRIM45 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249403

TRIM45 Antibody, RING finger protein 99 Antibody, RNF99 Antibody, Tripartite motif containing 45 Antibody, Tripartite motif-containing 45 Antibody Description: May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TRIM45, Monoclonal Antibody
Full Product Name
Anti-TRIM45 Antibody (clone 3G3) IHC-plus
Product Gene Name
Product Synonym Names
Mouse Monoclonal [clone 3G3] (IgG1) to Human TRIM45; Human TRIM45; TRIM45; RING finger protein 99; RNF99; Tripartite motif containing 45; Tripartite motif-containing 45
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3G3
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Purity/Purification
Protein A/G purified
Concentration
1 mg/ml (lot specific)
Specificity
Human TRIM45
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
62,475 Da
OMIM
609318
3D Structure
ModBase 3D Structure for Q9H8W5
Immunogen
TRIM45 antibody was raised against human recombinant protein fragment corresponding to amino acids 288-580 of human TRIM45(NP_079464) produced in E Coli.
Immunogen Description
Human recombinant protein fragment corresponding to amino acids 288-580 of human TRIM45(NP_079464) produced in E Coli.
Immunogen Type
Recombinant protein
Target Species
Human
Applications Tested/Suitable for anti-TRIM45 antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF)
Application Notes for anti-TRIM45 antibody
IF (1:100)
IHC-P (10 ug/ml)

Immunohistochemistry (IHC) of anti-TRIM45 antibody

Anti-TRIM45 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Mouse Anti-TRIM45 Monoclonal Antibody – Cat# MBS249403

Immunofluorescence (IF) of anti-TRIM45 antibody

Anti-TRIM45 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TRIM45.
Mouse Anti-TRIM45 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS249403

Other Notes

Small volumes of anti-TRIM45 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRIM45 purchase

MBS249403 is an antibody targeting TRIM45. Also known as Anti-TRIM45 Antibody (clone 3G3) IHC-plus. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TRIM45. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tripartite motif-containing protein 45 isoform 1
NCBI Official Synonym Full Names
tripartite motif containing 45
NCBI Official Symbol
TRIM45
NCBI Official Synonym Symbols
RNF99
UniProt Protein Name
Tripartite motif-containing protein 45
UniProt Synonym Protein Names
RING finger protein 99
UniProt Gene Name
TRIM45
UniProt Synonym Gene Names
RNF99
UniProt Entry Name
TRI45_HUMAN
NCBI Protein Information
tripartite motif-containing protein 45

NCBI Summary for TRIM45

This gene encodes a member of the tripartite motif family. The encoded protein may function as a transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2009]

UniProt Comments for TRIM45

TRIM45: May act as a transcriptional repressor in mitogen- activated protein kinase signaling pathway. Belongs to the TRIM/RBCC family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 1p13.1

Cellular Component: cytoplasm; intercellular bridge; nucleoplasm

Molecular Function: zinc ion binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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