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Peripherin (PRPH) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249795

PRPH Antibody, NEF4 Antibody, Neurofilament 4 (57kD) Antibody, Peripherin Antibody, PRPH1 Antibody, Neurofilament 4 Antibody Description: Peripherin is a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
Peripherin (PRPH), Polyclonal Antibody
Full Product Name
Anti-Peripherin Antibody (Internal) IHC-plus
Product Gene Name
Product Synonym Names
Rabbit Polyclonal (IgG) to Human Peripherin; Human Peripherin; NEF4; Neurofilament 4 (57kD); Peripherin; PRPH1; Neurofilament 4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Predicted Reactivity: Mouse, Rat, Bovine (at least 90% immunogen sequence identity)
Form/Format
0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
Human Peripherin
Preparation and Storage
Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles.
Molecular Weight
53,779 Da
OMIM
170710
3D Structure
ModBase 3D Structure for P41219
Immunogen
Peripherin antibody was raised against recombinant protein encompassing a sequence within the center region of human Peripherin.
Immunogen Description
Recombinant protein encompassing a sequence within the center region of human Peripherin.
Immunogen Type
Recombinant protein
Antigen Modification
Internal
Target Species
Human
Applications Tested/Suitable for anti-PRPH antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-PRPH antibody
IHC-P (10 ug/ml)
WB (1:500 - 1:3000)

Immunohistochemistry - Paraffin (IHC) of anti-PRPH antibody

Human Colon, Myenteric Plexus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-PRPH Polyclonal Antibody – Cat# MBS249795

Western Blot (WB) of anti-PRPH antibody

Sample (30 ug of whole cell lysate). A: Hela. 10% SDS PAGE. Peripherin antibody. Peripherin antibody diluted at 1:1000.
Rabbit Anti-PRPH Polyclonal Antibody, Western Blot (WB) – Cat# MBS249795

Other Notes

Small volumes of anti-PRPH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRPH purchase

MBS249795 is an antibody targeting PRPH. Also known as Anti-Peripherin Antibody (Internal) IHC-plus. Reactive in Human
Predicted Reactivity: Mouse, Rat, Bovine (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PRPH. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
peripherin
NCBI Official Synonym Full Names
peripherin
NCBI Official Symbol
PRPH
NCBI Official Synonym Symbols
NEF4; PRPH1
UniProt Protein Name
Peripherin
UniProt Synonym Protein Names
Neurofilament 4
Protein Family
UniProt Gene Name
PRPH
UniProt Synonym Gene Names
NEF4; PRPH1
UniProt Entry Name
PERI_HUMAN
NCBI Protein Information
peripherin

NCBI Summary for PRPH

This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008]
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UniProt Comments for PRPH

peripherin: Class-III neuronal intermediate filament protein. Belongs to the intermediate filament family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 12q12-q13

Cellular Component: intermediate filament; membrane; neurofilament; type III intermediate filament

Molecular Function: protein heterodimerization activity; structural molecule activity

Biological Process: intermediate filament cytoskeleton organization and biogenesis

Disease: Amyotrophic Lateral Sclerosis 1
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PRPH antibody

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