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AMIGO Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249950

AMIGO1 Antibody, ALI2 Antibody, AMIGO-1 Antibody, Amphoterin-induced protein 1 Antibody, KIAA1163 Antibody, Alivin-2 Antibody, AMIGO Antibody Description: Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in… More details

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Technical Datasheet View PDF
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Product Overview

Product Name
AMIGO, Polyclonal Antibody
Full Product Name
Anti-AMIGO Antibody (C-Terminus) IHC-plus
Product Gene Name
anti-AMIGO antibody
Product Synonym Gene Name
AMIGO1
Product Synonym Names
Rabbit Polyclonal (IgG) to Human AMIGO; Human AMIGO; ALI2; AMIGO-1; Amphoterin-induced protein 1; KIAA1163; Alivin-2; AMIGO
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat, Human
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
AMIGO1 antibody is human, mouse, and rat reactive. AMIGO1 antibody is predicted to not cross-react with AMIGO2 or AMIGO3.
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
Molecular Weight
55,239 Da
OMIM
615689
3D Structure
ModBase 3D Structure for Q86WK6
Immunogen
AMIGO antibody was raised against 19 amino acid peptide near the carboxy terminus of human AMIGO1.
Immunogen Description
19 amino acid peptide near the carboxy terminus of human AMIGO1.
Antigen Modification
C-Terminus
Target Species
Human
Applications Tested/Suitable for anti-AMIGO antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-AMIGO antibody
IF (20 ug/ml)
IHC-P (10 ug/ml)
WB (1 - 2 ug/ml)

Immunohistochemistry (IHC) of anti-AMIGO antibody

Anti-AMIGO antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-AMIGO Polyclonal Antibody – Cat# MBS249950

Immunohistochemistry (IHC) of anti-AMIGO antibody

Anti-AMIGO antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-AMIGO Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS249950

Immunofluorescence (IF) of anti-AMIGO antibody

Immunofluorescence of AMIGO1 in human brain tissue with AMIGO1 antibody at 20 µg/mL.
Rabbit Anti-AMIGO Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS249950

Western Blot (WB) of anti-AMIGO antibody

Western blot analysis of AMIGO1 in HeLa cell lysate with AMIGO1 antibody at (A) 1 and (B) 2 ug/ml.
Rabbit Anti-AMIGO Polyclonal Antibody, Western Blot (WB) – Cat# MBS249950

Other Notes

Small volumes of anti-AMIGO antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AMIGO purchase

MBS249950 is an antibody targeting AMIGO. Also known as Anti-AMIGO Antibody (C-Terminus) IHC-plus. Reactive in Mouse, Rat, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AMIGO. It may not necessarily be applicable to this product.

NCBI GI #
68052342
NCBI GeneID
57463
NCBI Accession #
Q86WK6.1
UniProt Primary Accession #
Q86WK6
UniProt Secondary Accession #
Q8IW71; Q9ULQ7; B4DIM3
UniProt Related Accession #
Q86WK6
NCBI Official Full Name
Amphoterin-induced protein 1
NCBI Official Synonym Full Names
adhesion molecule with Ig-like domain 1
NCBI Official Symbol
AMIGO1
NCBI Official Synonym Symbols
ALI2; AMIGO; AMIGO-1
UniProt Protein Name
Amphoterin-induced protein 1
UniProt Synonym Protein Names
AMIGO-1; Alivin-2
Protein Family
Amphoterin-induced protein
UniProt Gene Name
AMIGO1
UniProt Entry Name
AMGO1_HUMAN
NCBI Protein Information
amphoterin-induced protein 1

UniProt Comments for AMIGO

AMIGO1: Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Belongs to the immunoglobulin superfamily. AMIGO family.

Protein type: Cell development/differentiation; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: axon; dendrite; perikaryon; voltage-gated potassium channel complex

Molecular Function: potassium channel regulator activity

Biological Process: axonal fasciculation; axonogenesis; heterophilic cell adhesion; homophilic cell adhesion; myelination; positive regulation of axonogenesis; positive regulation of synaptogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AMIGO antibody

 Reference Product  PubMed Publications
 HMGB1 antibody  >4 publications with AMIGO and HMGB1
 AMIGO2 antibody  >1 publications with AMIGO and AMIGO2
 AMIGO3 antibody  >1 publications with AMIGO and AMIGO3

Diseases associated with anti-AMIGO antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with AMIGO and Nervous System Diseases

Organs/Tissues associated with anti-AMIGO antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with AMIGO and Brain
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