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CYP2U1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249956

CYP2U1 Antibody, p450TEC Antibody, SPG49 Antibody, Cytochrome P450 2U1 Antibody Description: Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a… More details

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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
CYP2U1, Polyclonal Antibody
Full Product Name
Anti-CYP2U1 Antibody (aa281-330) IHC-plus
Product Gene Name
Product Synonym Names
Rabbit Polyclonal (IgG) to Human CYP2U1; Human CYP2U1; p450TEC; SPG49; Cytochrome P450 2U1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat, Human
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
Cytochrome P450 2U1 Antibody detects endogenous levels of total Cytochrome P450 2U1 protein.
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
18,578 Da
OMIM
610670
3D Structure
ModBase 3D Structure for Q7Z449
Immunogen
CYP2U1 antibody was raised against synthetic peptide from human Cytochrome P450 2U1 (aa281-330).
Immunogen Description
Synthetic peptide from human Cytochrome P450 2U1 (aa281-330).
Antigen Modification
aa281-330
Target Species
Human
Applications Tested/Suitable for anti-CYP2U1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes for anti-CYP2U1 antibody
ELISA (1:20000)
IHC-P (10 ug/ml)
WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-CYP2U1 antibody

Anti-CYP2U1 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-CYP2U1 Polyclonal Antibody – Cat# MBS249956

Western Blot (WB) of anti-CYP2U1 antibody

Western blot of extracts from HeLa/Lovo cells, using Cytochrome P450 2U1 Antibody. The lane on the right is treated with the synthesized peptide.
Rabbit Anti-CYP2U1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS249956

Other Notes

Small volumes of anti-CYP2U1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CYP2U1 purchase

MBS249956 is an antibody targeting CYP2U1. Also known as Anti-CYP2U1 Antibody (aa281-330) IHC-plus. Reactive in Mouse, Rat, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CYP2U1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cytochrome P450 2U1
NCBI Official Synonym Full Names
cytochrome P450 family 2 subfamily U member 1
NCBI Official Symbol
CYP2U1
NCBI Official Synonym Symbols
SPG49; SPG56; P450TEC
UniProt Protein Name
Cytochrome P450 2U1
Protein Family
UniProt Gene Name
CYP2U1
UniProt Entry Name
CP2U1_HUMAN
NCBI Protein Information
cytochrome P450 2U1

NCBI Summary for CYP2U1

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids. [provided by RefSeq, Jul 2008]
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UniProt Comments for CYP2U1

CYP2U1: Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. Belongs to the cytochrome P450 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; Membrane protein, integral; Lipid Metabolism - arachidonic acid; Membrane protein, multi-pass; EC 1.14.14.1

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: heme binding; iron ion binding; steroid hydroxylase activity

Biological Process: arachidonic acid metabolic process; xenobiotic metabolic process

Disease: Spastic Paraplegia 56, Autosomal Recessive
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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