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GATA5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2529818

The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the… More details

$160 / 0.02 mL +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GATA5, Polyclonal Antibody
Full Product Name
GATA5 Polyclonal Antibody
Product Gene Name
anti-GATA5 antibody
Product Synonym Names
GATAS; bB379O24.1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
3.2mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
41,299 Da
OMIM
611496
Immunogen
Synthetic peptide of human GATA5
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3

Product Categories/Family for anti-GATA5 antibody

Epigenetics
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GATA5 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-GATA5 antibody
IHC: 1:50-1:200

Immunohistochemistry (IHC) of anti-GATA5 antibody

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using GATA5 Polyclonal Antibody at dilution 1:50
Rabbit Anti-GATA5 Polyclonal Antibody – Cat# MBS2529818

Immunohistochemistry (IHC) of anti-GATA5 antibody

Immunohistochemistry of paraffin-embedded Human brain tissue using GATA5 Polyclonal Antibody at dilution 1:50
Rabbit Anti-GATA5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2529818

Other Notes

Small volumes of anti-GATA5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GATA5 purchase

MBS2529818 is an antibody targeting GATA5. Also known as GATA5 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GATA5. It may not necessarily be applicable to this product.

NCBI GI #
29126838
NCBI GeneID
140628
NCBI Accession #
AAH47790.1
UniProt Secondary Accession #
Q17RE2; Q86VU4; D9ZGF7
UniProt Related Accession #
Q9BWX5
NCBI Official Full Name
GATA5 protein, partial
NCBI Official Synonym Full Names
GATA binding protein 5
NCBI Official Symbol
GATA5
NCBI Official Synonym Symbols
GATAS; bB379O24.1
UniProt Protein Name
Transcription factor GATA-5
UniProt Synonym Protein Names
GATA-binding factor 5
Protein Family
GATA transcription factor
UniProt Gene Name
GATA5
UniProt Entry Name
GATA5_HUMAN
NCBI Protein Information
transcription factor GATA-5; GATA binding factor-5; GATA-binding factor 5; GATA-binding protein 5

UniProt Comments for GATA5

GATA5: Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer. May play an important role in the transcriptional program(s) that underlies smooth muscle cell diversity. Rare variants in GATA5 may be a cause of susceptibility to atrial fibrillation, a common sustained cardiac rhythm disturbance. Atrial fibrillation is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure.

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: nucleoplasm; nucleus

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; zinc ion binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; blood coagulation
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Research Articles on GATA5

1. study provides genetic evidence on the association of GATA5 loss-of-function mutations with enhanced susceptibility to bicuspid aortic valve (BAV), providing novel insight into the molecular mechanism involved in human BAV

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GATA5 antibody

 Reference Product  PubMed Publications
 GATA4 antibody  >73 publications with GATA5 and GATA4
 GATA6 antibody  >58 publications with GATA5 and GATA6
 GATA2 antibody  >6 publications with GATA5 and GATA2
 HEY2 antibody  >1 publications with GATA5 and HEY2
 ZFPM1 antibody  >1 publications with GATA5 and ZFPM1

Pathways associated with anti-GATA5 antibody

 Products by Pathway  Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram

Diseases associated with anti-GATA5 antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >24 publications with GATA5 and Carcinoma
 Lung Neoplasms Antibodies  >10 publications with GATA5 and Lung Neoplasms
 Colorectal Neoplasms Antibodies  >6 publications with GATA5 and Colorectal Neoplasms
 Neoplasms, Experimental Antibodies  >3 publications with GATA5 and Neoplasms, Experimental
 Ovarian Neoplasms Antibodies  >3 publications with GATA5 and Ovarian Neoplasms
 Inflammation Antibodies  >3 publications with GATA5 and Inflammation
 Leukemia Antibodies  >2 publications with GATA5 and Leukemia
 Breast Neoplasms Antibodies  >2 publications with GATA5 and Breast Neoplasms
 Anemia Antibodies  >1 publications with GATA5 and Anemia
 Fatty Liver Antibodies  >1 publications with GATA5 and Fatty Liver

Organs/Tissues associated with anti-GATA5 antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >39 publications with GATA5 and Embryonic Tissue
 Lung Antibodies  >21 publications with GATA5 and Lung
 Kidney Antibodies  >5 publications with GATA5 and Kidney
 Uterus Antibodies  >1 publications with GATA5 and Uterus
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