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DHRS4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2547620

MBS2547620 is an antibody targeting DHRS4. Also known as DHRS4 Polyclonal Antibody. Host: Rabbit. More details

$205 / 0.06 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DHRS4, Polyclonal Antibody
Full Product Name
DHRS4 Polyclonal Antibody
Product Gene Name
anti-DHRS4 antibody
Product Synonym Names
CR; NRDR; PHCR; PSCD; SDR-SRL; SDR25C1; SDR25C2; SCAD-SRL
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
30kDa
OMIM
AF044127 mRNA
3D Structure
ModBase 3D Structure for Q9BTZ2
Immunogen
Recombinant protein of human DHRS4
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-DHRS4 antibody
Western Blot (WB)
Application Notes for anti-DHRS4 antibody
WB: 1:500 - 1:2000

Other Notes

Small volumes of anti-DHRS4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DHRS4. It may not necessarily be applicable to this product.

NCBI GI #
545479056
NCBI GeneID
10901
NCBI Accession #
NP_001269916.1
UniProt Primary Accession #
Q9BTZ2
UniProt Secondary Accession #
O95162; Q20CR0; Q2LC19; Q2LE81; Q58IU4; Q6E0Y1; Q6UWU3; B2RB10; B7WNS9; D3YTB8; E2QRL8
UniProt Related Accession #
Q9BTZ2
GenBank Nucleotide #
NM_001282987.1
NCBI Official Full Name
dehydrogenase/reductase SDR family member 4 isoform 2
NCBI Official Synonym Full Names
dehydrogenase/reductase 4
NCBI Official Symbol
DHRS4
NCBI Official Synonym Symbols
CR; NRDR; PHCR; PSCD; SDR-SRL; SDR25C1; SDR25C2; SCAD-SRL
UniProt Protein Name
Dehydrogenase/reductase SDR family member 4
UniProt Synonym Protein Names
NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; CR; PHCR; NADPH-dependent retinol dehydrogenase/reductase; NRDR; humNRDR; Peroxisomal short-chain alcohol dehydrogenase; PSCD; SCAD-SRL; Short chain dehydrogenase/reductase family 25C member 2; Short-chain dehydrogenase/reductase family member 4
Protein Family
Putative uncharacterized protein
UniProt Gene Name
DHRS4
UniProt Synonym Gene Names
SDR25C2; CR; PHCR; NRDR; humNRDR; PSCD
NCBI Protein Information
dehydrogenase/reductase SDR family member 4

UniProt Comments for DHRS4

DHRS4: Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co- factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.184; Mitochondrial; Nuclear envelope; Oxidoreductase

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: endoplasmic reticulum membrane; mitochondrion; peroxisomal membrane; peroxisome

Molecular Function: 3-keto sterol reductase activity; alcohol dehydrogenase [NAD(P)+] activity; carbonyl reductase (NADPH) activity; oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; receptor binding

Biological Process: alcohol metabolic process; ketone metabolic process; protein tetramerization; steroid metabolic process
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Research Articles on DHRS4

1. An analysis of the relationship between the promoter characteristics and RNA expression of the DHRS4 gene cluster indicated that the development of CpG islands, in addition to the promoter sequence, during mammalian evolution could modulate the dose compensatory regulation of the copy number-varied DHRS4 gene cluster
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-DHRS4 antibody

 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 RA Biosynthesis Pathway antibodies  RA Biosynthesis Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Retinoic Acid Pathway antibodies  Signaling By Retinoic Acid Pathway Diagram
 Retinol Biosynthesis Pathway antibodies  Retinol Biosynthesis Pathway Diagram
 The Visual Cycle I (vertebrates) Pathway antibodies  The Visual Cycle I (vertebrates) Pathway Diagram

Diseases associated with anti-DHRS4 antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >1 publications with DHRS4 and Liver Diseases
 Liver Neoplasms Antibodies  >1 publications with DHRS4 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with DHRS4 and Carcinoma, Hepatocellular

Organs/Tissues associated with anti-DHRS4 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with DHRS4 and Liver
 Testis Antibodies  >2 publications with DHRS4 and Testis
 Eye Antibodies  >1 publications with DHRS4 and Eye
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