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ENSA Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2560774

The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ENSA, Polyclonal Antibody
Full Product Name
ENSA Polyclonal Antibody
Product Gene Name
anti-ENSA antibody
Product Synonym Names
Alpha endosulfine; ARPP 19e; Endosulfine alpha
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
0.72mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
OMIM
603061
3D Structure
ModBase 3D Structure for O43768
Immunogen
Fusion protein of human ENSA
Conjugation
Unconjugated

Product Categories/Family for anti-ENSA antibody

Neuroscience
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ENSA antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-ENSA antibody
IHC: 1:40-1:200
ELISA: 1:5000-1:10000

Immunohistochemistry (IHC) of anti-ENSA antibody

Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ENSA Polyclonal Antibody at dilution of 1:40(×200)
Rabbit Anti-ENSA Polyclonal Antibody – Cat# MBS2560774

Immunohistochemistry (IHC) of anti-ENSA antibody

Immunohistochemistry of paraffin-embedded Human tonsil tissue using ENSA Polyclonal Antibody at dilution of 1:40(×200)
Rabbit Anti-ENSA Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2560774

Other Notes

Small volumes of anti-ENSA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ENSA purchase

MBS2560774 is an antibody targeting ENSA. Also known as ENSA Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ENSA. It may not necessarily be applicable to this product.

NCBI GI #
4758272
NCBI GeneID
2029
NCBI Accession #
NP_004427.1
NCBI Related Accession #
BC000436
UniProt Primary Accession #
O43768
UniProt Related Accession #
O43768
GenBank Nucleotide #
NP_004427.1
NCBI Official Full Name
alpha-endosulfine isoform 3
NCBI Official Synonym Full Names
endosulfine alpha
NCBI Official Symbol
ENSA
NCBI Official Synonym Symbols
ARPP-19e
UniProt Protein Name
Alpha-endosulfine
UniProt Synonym Protein Names
ARPP-19e
Protein Family
Alpha-endosulfine
UniProt Gene Name
ENSA
UniProt Entry Name
ENSA_HUMAN
NCBI Protein Information
alpha-endosulfine

UniProt Comments for ENSA

ENSA: a cytoplasmic, highly conserved cAMP-regulated phosphoprotein (ARPP) and regulator of ATP-sensitive potassium (KATP) channels. An endogenous ligand for the sulfonylurea receptor, ABCC8, the regulatory subunit of the KATP channel located on the plasma membrane of pancreatic beta cells. Modulates insulin secretion through the interaction with ABCC8, and may be associated with type 2 diabetes. Eight alternatively spliced isoforms have been observed.

Protein type: Inhibitor

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: nucleoplasm; cytoplasm

Molecular Function: phosphatase inhibitor activity; protein phosphatase 2A binding; protein phosphatase type 2A regulator activity; protein phosphatase inhibitor activity; potassium channel inhibitor activity; ion channel inhibitor activity; receptor binding

Biological Process: mitosis; regulation of catalytic activity; transport; cell division; negative regulation of catalytic activity; response to glucose stimulus; mitotic cell cycle; G2/M transition of mitotic cell cycle; regulation of insulin secretion; response to nutrient
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Research Articles on ENSA

1. The extended S phase in Ensa-depleted cells is completely rescued by the overexpression of Treslin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ENSA antibody

 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 M Phase Pathway antibodies  M Phase Pathway Diagram
 MASTL Facilitates Mitotic Progression Pathway antibodies  MASTL Facilitates Mitotic Progression Pathway Diagram
 Mitotic Prophase Pathway antibodies  Mitotic Prophase Pathway Diagram

Diseases associated with anti-ENSA antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >5 publications with ENSA and Liver Diseases
 Nervous System Diseases Antibodies  >4 publications with ENSA and Nervous System Diseases
 Liver Neoplasms Antibodies  >4 publications with ENSA and Liver Neoplasms
 Disease Models, Animal Antibodies  >2 publications with ENSA and Disease Models, Animal
 Kidney Neoplasms Antibodies  >2 publications with ENSA and Kidney Neoplasms
 Heart Diseases Antibodies  >2 publications with ENSA and Heart Diseases
 Kidney Diseases Antibodies  >2 publications with ENSA and Kidney Diseases
 Neoplasm Metastasis Antibodies  >1 publications with ENSA and Neoplasm Metastasis
 Carcinoma Antibodies  >1 publications with ENSA and Carcinoma
 Fatty Liver Antibodies  >1 publications with ENSA and Fatty Liver

Organs/Tissues associated with anti-ENSA antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >11 publications with ENSA and Blood
 Liver Antibodies  >10 publications with ENSA and Liver
 Adipose Tissue Antibodies  >7 publications with ENSA and Adipose Tissue
 Muscle Antibodies  >7 publications with ENSA and Muscle
 Kidney Antibodies  >7 publications with ENSA and Kidney
 Connective Tissue Antibodies  >5 publications with ENSA and Connective Tissue
 Heart Antibodies  >4 publications with ENSA and Heart
 Thyroid Antibodies  >4 publications with ENSA and Thyroid
 Brain Antibodies  >3 publications with ENSA and Brain
 Vascular Antibodies  >2 publications with ENSA and Vascular
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