Rabbit Anti-CPLX1 Polyclonal Antibody – Cat# MBS2560780

Immunohistochemistry of paraffin-embedded Human tonsil tissue using CPLX1 Polyclonal Antibody at dilution of 1:30(×200)

CPLX1 Antibody – Rabbit Polyclonal

Name: CPLX1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2560780
Price: 160 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2560780

Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and… More details

$160 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CPLX1, Polyclonal Antibody

Full Product Name

CPLX1 Polyclonal Antibody

Product Gene Name

anti-CPLX1 antibody

Product Synonym Names

921-S; Complexin 1; Complexin I; Complexin-1; CPLX1; CPLX1; CPX I; CPX-I; CPX1; Synaphin 2; Synaphin-2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purity/Purification

Antigen Affinity Purification

Concentration

0.48mg/mL (lot specific)

Preparation and Storage

Store at -20 degree C. Avoid freeze/thaw cycles.

OMIM

605032

3D Structure

ModBase 3D Structure for O14810

Immunogen

Fusion protein of human CPLX1

Conjugation

Unconjugated

Product Categories/Family for anti-CPLX1 antibody

Neuroscience; Signal Transduction

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-CPLX1 antibody

Immunohistochemistry (IHC), ELISA (EIA)

Application Notes for anti-CPLX1 antibody

IHC: 1:10-1:50
ELISA: 1:5000-1:10000

Other Notes

Small volumes of anti-CPLX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CPLX1 purchase

MBS2560780 is an antibody targeting CPLX1. Also known as CPLX1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CPLX1. It may not necessarily be applicable to this product.

NCBI GI #

5729781

NCBI GeneID

10815

NCBI Accession #

NP_006642.1

NCBI Related Accession #

BC002471

UniProt Primary Accession #

O14810

UniProt Related Accession #

O14810

GenBank Nucleotide #

NP_006642.1

NCBI Official Full Name

complexin-1

NCBI Official Synonym Full Names

complexin 1

NCBI Official Symbol

CPLX1

NCBI Official Synonym Symbols

CPX1; CPX-I; EIEE63

UniProt Protein Name

Complexin-1

UniProt Synonym Protein Names

Complexin I; CPX I; Synaphin-2

UniProt Gene Name

CPLX1

UniProt Synonym Gene Names

CPX I

UniProt Entry Name

CPLX1_HUMAN

NCBI Protein Information

complexin-1

UniProt Comments for CPLX1

CPLX1: Positively regulates a late step in synaptic vesicle exocytosis. Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Belongs to the complexin/synaphin family.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 4p16.3

Cellular Component: cell soma; dendrite; synapse; cytosol

Molecular Function: syntaxin-1 binding; neurotransmitter transporter activity

Biological Process: regulation of exocytosis; synaptic transmission; synaptic vesicle exocytosis; exocytosis; glutamate secretion; insulin secretion; neurotransmitter secretion

Disease: Wolf-hirschhorn Syndrome

Research Articles on CPLX1

1. Findings do not support microRNA137 (MIR137) and complexin 1 (CPLX1) conferring susceptibility to schizophrenia in Han Chinese.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CPLX1 antibody

Reference Product	PubMed Publications
SNAP25 antibody	>2 publications with CPLX1 and SNAP25
VAMP2 antibody	>2 publications with CPLX1 and VAMP2
STX1A antibody	>2 publications with CPLX1 and STX1A
RAB3A antibody	>1 publications with CPLX1 and RAB3A
SYT1 antibody	>1 publications with CPLX1 and SYT1

Pathways associated with anti-CPLX1 antibody

Products by Pathway	Pathway Diagram
Acetylcholine Neurotransmitter Release Cycle Pathway antibodies	Acetylcholine Neurotransmitter Release Cycle Pathway Diagram
Dopamine Neurotransmitter Release Cycle Pathway antibodies	Dopamine Neurotransmitter Release Cycle Pathway Diagram
GABA Synthesis, Release, Reuptake And Degradation Pathway antibodies	GABA Synthesis, Release, Reuptake And Degradation Pathway Diagram
Glutamate Neurotransmitter Release Cycle Pathway antibodies	Glutamate Neurotransmitter Release Cycle Pathway Diagram
Neuronal System Pathway antibodies	Neuronal System Pathway Diagram
Neurotransmitter Release Cycle Pathway antibodies	Neurotransmitter Release Cycle Pathway Diagram
Norepinephrine Neurotransmitter Release Cycle Pathway antibodies	Norepinephrine Neurotransmitter Release Cycle Pathway Diagram
Serotonin Neurotransmitter Release Cycle Pathway antibodies	Serotonin Neurotransmitter Release Cycle Pathway Diagram
Synaptic Vesicle Pathway antibodies	Synaptic Vesicle Pathway Diagram
Synaptic Vesicle Cycle Pathway antibodies	Synaptic Vesicle Cycle Pathway Diagram

Diseases associated with anti-CPLX1 antibody

Disease Name	Pubmed Publications
Schizophrenia Antibodies	>8 publications with CPLX1 and Schizophrenia
Mental Disorders Antibodies	>6 publications with CPLX1 and Mental Disorders
Nervous System Diseases Antibodies	>5 publications with CPLX1 and Nervous System Diseases
Brain Diseases Antibodies	>3 publications with CPLX1 and Brain Diseases
Memory Disorders Antibodies	>3 publications with CPLX1 and Memory Disorders
Learning Disorders Antibodies	>2 publications with CPLX1 and Learning Disorders
Cognition Disorders Antibodies	>2 publications with CPLX1 and Cognition Disorders
Atrophy Antibodies	>2 publications with CPLX1 and Atrophy
Depressive Disorder Antibodies	>2 publications with CPLX1 and Depressive Disorder
Growth Disorders Antibodies	>2 publications with CPLX1 and Growth Disorders

Organs/Tissues associated with anti-CPLX1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>9 publications with CPLX1 and Brain
Blood Antibodies	>1 publications with CPLX1 and Blood
Pancreas Antibodies	>1 publications with CPLX1 and Pancreas