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REXO2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2565420

This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation.… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
REXO2, Polyclonal Antibody
Full Product Name
REXO2 Polyclonal Antibody
Product Gene Name
Product Synonym Names
REXO2; CGI-114; REX2; RFN; SFN
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purity/Purification
Affinity purification
Concentration
1mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
23,754 Da
OMIM
607149
3D Structure
ModBase 3D Structure for Q9Y3B8
Immunogen
Recombinant fusion protein of human REXO2 (NP_0563382)
Conjugation
Unconjugated

Product Categories/Family for anti-REXO2 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-REXO2 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-REXO2 antibody
WB: 1:500-1:2000
IF: 1:50-1:100

Western Blot (WB) of anti-REXO2 antibody

Western blot analysis of extracts of various cell lines using REXO2 Polyclonal Antibody at dilution of 1:1000.
Rabbit Anti-REXO2 Polyclonal Antibody – Cat# MBS2565420

Immunofluorescence (IF) of anti-REXO2 antibody

Immunofluorescence analysis of L929 cells using REXO2 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Rabbit Anti-REXO2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS2565420

Immunofluorescence (IF) of anti-REXO2 antibody

Immunofluorescence analysis of U-2 OS cells using REXO2 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Rabbit Anti-REXO2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS2565420

Other Notes

Small volumes of anti-REXO2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for REXO2 purchase

MBS2565420 is an antibody targeting REXO2. Also known as REXO2 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for REXO2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens RNA exonuclease 2 (REXO2), mRNA
NCBI Official Synonym Full Names
RNA exonuclease 2
NCBI Official Symbol
REXO2
NCBI Official Synonym Symbols
RFN; SFN; REX2; CGI-114
UniProt Protein Name
Oligoribonuclease, mitochondrial
UniProt Synonym Protein Names
RNA exonuclease 2 homolog; Small fragment nuclease
UniProt Gene Name
REXO2
UniProt Synonym Gene Names
SFN; SMFN
UniProt Entry Name
ORN_HUMAN
NCBI Protein Information
oligoribonuclease, mitochondrial; REX2, RNA exonuclease 2 homolog; small fragment nuclease

UniProt Comments for REXO2

REXO2: a 3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. May have a role for cellular nucleotide recycling. Two splice variant isoforms have been described: mitochondrial (isoform 1) and nuclear (isoform 2).

Protein type: EC 3.1.-.-; Hydrolase

Chromosomal Location of Human Ortholog: 11q23.2

Cellular Component: focal adhesion; mitochondrion; mitochondrial matrix; nucleolus; mitochondrial intermembrane space; nucleus

Molecular Function: 3'-5'-exoribonuclease activity; nucleic acid binding; 3'-5' exonuclease activity

Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; nucleotide metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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