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8- (3- Butynylthio)guanosine- 3', 5'- cyclic monophosphate (8-Bu(3-yne)T-cGMP), sodium salt

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS256646

Functionalized cGMP analogue for "click chemistry" reactions. Functionalized cGMP analogue with a terminal alkyne group which can be used for copper-catalyzed azide-alkynecycloaddition (CuAAC) "click chemistry" reactions with azide-containing molecules. More details

$615 / 1 umol +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
8- (3- Butynylthio)guanosine- 3', 5'- cyclic monophosphate (8-Bu(3-yne)T-cGMP), Biochemical
Full Product Name
8- (3- Butynylthio)guanosine- 3', 5'- cyclic monophosphate (8-Bu(3-yne)T-cGMP), sodium salt
Product Synonym Names
8-Bu(3-yne)T-cGMP
Form/Format
Sodium. Lyophilized or crystallized sodium salt.
Purity/Purification
Typical analysis is >95% (HPLC/ UV/ 275 nm). The product is not sterile and has not been tested for endotoxins.
Preparation and Storage
Store at -20 degree C
It has sufficient stability at room temperature and does not need special care during handling or shipment. Nevertheless, we recommend that the compound should be stored in the freezer, for longer storage periods preferably in freeze-dried form.
Molecular Weight
451.3
Solubility
8-Bu(3-yne)T-cGMP is soluble in water, limits have not been determined.
SMILES
NC(NC1=O)=NC2=C1N=C(SCCC#C)N2[C@H]3[C@H](O)[C@H](O4)[C@@H](COP4([O-])=O)O3.[Na+]
CAS Number
2201859-36-9
Formula
C??H??N?O?PS·Na
Properties
Functionalized cGMP analogue for "click chemistry" reactions.
UV
lambda max 275 nm, epsilon 14000, pH 7
Notes
Please keep in mind that equal amounts of the compound may look different in volume. Micromolar quantities are determined by weight. The compound can even contract to small volume droplets. Normally the product is located in the conical bottom of the tube.
Please rinse tube walls carefully and preferably use ultrasonic or vortex to achieve total and uniform mixing. When opening the tube please make sure that no substance is lost within the cap.
Please keep in mind that the in vivo properties of this compound are not sufficiently characterized up to now.

Product References and Citations for 8- (3- Butynylthio)guanosine- 3', 5'- cyclic monophosphate (8-Bu(3-yne)T-cGMP) biochemical

1. Presolski, S.I.; Hong, V.P.; Finn, M.G., Curr. Protoc. Chem. Biol., 3, 153 - 162 (2011): "Copper-Catalyzed Azide-Alkyne ClickChemistry for Bioconjugation"
2. Hong, V.P.; Presolski, S.I.; Ma, C.; Finn, M.G., Angew. Chem. Int. Ed. Engl., 48, 9879 - 9883 (2009): "Analysis andoptimization of copper-catalyzed azide-alkyne cycloaddition for bioconjugation.

Other Notes

Small volumes of 8- (3- Butynylthio)guanosine- 3', 5'- cyclic monophosphate (8-Bu(3-yne)T-cGMP) biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 8- (3- Butynylthio)guanosine- 3', 5'- cyclic monophosphate (8-Bu(3-yne)T-cGMP) purchase

MBS256646 is a biochemical targeting 8- (3- Butynylthio)guanosine- 3', 5'- cyclic monophosphate (8-Bu(3-yne)T-cGMP). Also known as 8- (3- Butynylthio)guanosine- 3', 5'- cyclic monophosphate (8-Bu(3-yne)T-cGMP), sodium salt.
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