Potassium Voltage-Gated Channel Subfamily V Member 1 (KCNV1) ELISA Kit for Human

Name: Human KCNV1 ELISA Kit; MyBioSource
Brand: MyBioSource
SKU: MBS281538
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS281538

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate KCNV1 in samples. An antibody specific for KCNV1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyKCNV1 present is bound by the… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Potassium voltage-gated channel subfamily V member 1 (KCNV1), ELISA Kit

Full Product Name

Human Potassium voltage-gated channel subfamily V member 1 (KCNV1) ELISA Kit

Product Gene Name

KCNV1 elisa kit

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma, Other biological fluids

Specificity

This assay has high sensitivity and excellent specificity for detection of Human KCNV1. No significant cross-reactivity or interference between Human KCNV1 and analogues was observed.

Preparation and Storage

Store at 2-8 degree C.

Molecular Weight

56,304 Da

OMIM

AB032013 Genomic DNA

3D Structure

ModBase 3D Structure for Q6PIU1

Sample Volume

1-200 uL

Precision

Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV

Detection Wavelength

450 nm

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of KCNV1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KCNV1 purchase

MBS281538 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Potassium voltage-gated channel subfamily V member 1 (KCNV1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing KCNV1. The ELISA analytical biochemical technique of the MBS281538 kit is based on KCNV1 antibody-KCNV1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KCNV1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KCNV1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for KCNV1. It may not necessarily be applicable to this product.

NCBI GI #

7657289

NCBI GeneID

27012

NCBI Accession #

NP_055194.1

UniProt Primary Accession #

Q6PIU1

UniProt Secondary Accession #

Q9UHJ4

UniProt Related Accession #

Q6PIU1

GenBank Nucleotide #

NM_014379.3

NCBI Official Full Name

potassium voltage-gated channel subfamily V member 1

NCBI Official Synonym Full Names

potassium voltage-gated channel modifier subfamily V member 1

NCBI Official Symbol

KCNV1

NCBI Official Synonym Symbols

HNKA; KCNB3; KV2.3; KV8.1

UniProt Protein Name

Potassium voltage-gated channel subfamily V member 1

UniProt Synonym Protein Names

Neuronal potassium channel alpha subunit HNKA; Voltage-gated potassium channel subunit Kv8.1

Protein Family

Potassium voltage-gated channel subfamily

UniProt Gene Name

KCNV1

NCBI Protein Information

potassium voltage-gated channel subfamily V member 1

NCBI Summary for KCNV1

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This protein is essentially present in the brain, and its role might be to inhibit the function of a particular class of outward rectifier potassium channel types. [provided by RefSeq, Jul 2008]

UniProt Comments for KCNV1

KCNV1: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes. Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 8q23.2

Cellular Component: integral component of plasma membrane; plasma membrane; voltage-gated potassium channel complex

Molecular Function: ion channel inhibitor activity; potassium channel regulator activity; voltage-gated potassium channel activity

Biological Process: potassium ion transport; protein homooligomerization; regulation of molecular function

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with KCNV1 elisa kit

Reference Product	PubMed Publications
KCNB1 elisa kit	>2 publications with KCNV1 and KCNB1

Pathways associated with KCNV1 elisa kit

Products by Pathway	Pathway Diagram
Neuronal System Pathway antibodies	Neuronal System Pathway Diagram
Potassium Channels Pathway antibodies	Potassium Channels Pathway Diagram
Voltage Gated Potassium Channels Pathway antibodies	Voltage Gated Potassium Channels Pathway Diagram

Diseases associated with KCNV1 elisa kit

Disease Name	Pubmed Publications
Epilepsy Antibodies	>1 publications with KCNV1 and Epilepsy
Inflammation Antibodies	>1 publications with KCNV1 and Inflammation

Organs/Tissues associated with KCNV1 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with KCNV1 and Brain