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Bone Morphogenetic Protein Receptor Type-1a (BMPR1A) ELISA Kit for Rat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS289847

MBS289847 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Bone morphogenetic protein receptor type-1A (Bmpr1a) ELISA Kit target analytes in biological samples. The concentration… More details

$405 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Bone morphogenetic protein receptor type-1A (Bmpr1a), ELISA Kit
Full Product Name
Rat Bone morphogenetic protein receptor type-1A ELISA Kit
Product Gene Name
Bmpr1a elisa kit
Product Synonym Names
Bone morphogenetic protein receptor type-1A; BMP type-1A receptor; BMPR-1A; Activin receptor-like kinase 3; ALK-3; Bone morphogenetic protein 4 receptor; Bmpr1a; 2.7.11.30; CD292
Species Reactivity
Rat
Assay Type
Sandwich
Detection Range
0.78-50 ng/mL
Sensitivity
0.39 ng/mL
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Molecular Weight
59,994 Da
3D Structure
ModBase 3D Structure for Q78EA7
Intra-Assay CV
<=6.9%
Inter-Assay CV
<=9.3%
Recovery
98%

Typical Testing Data/Standard Curve (for reference only) of Bmpr1a elisa kit

Rat BMPR1A ELISA Kit – Cat# MBS289847

Other Notes

Small volumes of Bmpr1a elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Bmpr1a. It may not necessarily be applicable to this product.

NCBI GI #
13540661
NCBI GeneID
81507
NCBI Accession #
NP_110476.1
UniProt Primary Accession #
Q78EA7
UniProt Secondary Accession #
Q64308
UniProt Related Accession #
Q78EA7
GenBank Nucleotide #
NM_030849.1
NCBI Official Full Name
bone morphogenetic protein receptor type-1A
NCBI Official Synonym Full Names
bone morphogenetic protein receptor type 1A
NCBI Official Symbol
Bmpr1a
UniProt Protein Name
Bone morphogenetic protein receptor type-1A
UniProt Synonym Protein Names
Activin receptor-like kinase 3; ALK-3; Bone morphogenetic protein 4 receptor; CD_antigen: CD292
Protein Family
Bone morphogenetic protein receptor
UniProt Gene Name
Bmpr1a
UniProt Synonym Gene Names
BMP type-1A receptor; BMPR-1A; ALK-3
UniProt Entry Name
BMR1A_RAT
NCBI Protein Information
bone morphogenetic protein receptor type-1A

NCBI Summary for Bmpr1a

may act as a serine/threonine kinase receptor; may mediate bone morphogenetic protein-induced bone formation [RGD, Feb 2006]

UniProt Comments for Bmpr1a

BMPR1A: a serine/threonine-protein kinase receptor for Bone morphogenetic protein-2 and -4 (BMP-2 and BMP-4). Defects in BMPR1A are a cause of juvenile polyposis syndrome (JPS) and Cowden disease (CD), a cancer syndrome characterized by multiple hamartomas and by a high risk for breast, thyroid and endometriel cancers.

Protein type: Protein kinase, TKL; Membrane protein, integral; Kinase, protein; EC 2.7.11.30; Protein kinase, Ser/Thr (receptor); TKL group; STKR family; Type1 subfamily

Cellular Component: caveola; cell soma; dendrite; external side of plasma membrane; integral to membrane; plasma membrane

Molecular Function: ATP binding; glycoprotein binding; metal ion binding; protein homodimerization activity; protein serine/threonine kinase activity; receptor signaling protein serine/threonine kinase activity; SMAD binding; transmembrane receptor protein serine/threonine kinase activity

Biological Process: anterior/posterior pattern formation; BMP signaling pathway; cartilage development; cell differentiation; chondrocyte differentiation; developmental growth; dorsal/ventral axis specification; dorsal/ventral pattern formation; ectoderm development; embryonic digit morphogenesis; embryonic morphogenesis; embryonic organ development; endoderm development; heart development; heart morphogenesis; hindlimb morphogenesis; immune response; in utero embryonic development; lateral mesoderm development; lung development; mesendoderm development; mesoderm formation; Mullerian duct regression; negative regulation of neurogenesis; nervous system development; neural crest cell development; neural plate mediolateral pattern formation; odontogenesis of dentine-containing teeth; palate development; paraxial mesoderm development; paraxial mesoderm structural organization; pattern specification process; pituitary gland development; positive regulation of bone mineralization; positive regulation of epithelial cell proliferation; positive regulation of mesenchymal cell proliferation; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein amino acid phosphorylation; regulation of endothelial cell differentiation; regulation of endothelial cell proliferation; regulation of lateral mesodermal cell fate specification; somitogenesis; stem cell maintenance; transmembrane receptor protein serine/threonine kinase signaling pathway
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Research Articles on Bmpr1a

1. Expression of BMPR IA increases significantly in the astrocytes and activated microglia cells in rats after contusive spinal cord injury.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Bmpr1a elisa kit

 Reference Product  PubMed Publications
 Bmp2 elisa kit  >95 publications with Bmpr1a and Bmp2
 Bmp4 elisa kit  >82 publications with Bmpr1a and Bmp4
 Smad1 elisa kit  >80 publications with Bmpr1a and Smad1
 Bmp7 elisa kit  >40 publications with Bmpr1a and Bmp7
 Smad5 elisa kit  >32 publications with Bmpr1a and Smad5
 Bmp6 elisa kit  >18 publications with Bmpr1a and Bmp6
 Smad6 elisa kit  >14 publications with Bmpr1a and Smad6
 Gdf5 elisa kit  >13 publications with Bmpr1a and Gdf5
 Smad7 elisa kit  >10 publications with Bmpr1a and Smad7
 Smad9 elisa kit  >7 publications with Bmpr1a and Smad9

Pathways associated with Bmpr1a elisa kit

 Products by Pathway  Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By BMP Pathway antibodies  Signaling By BMP Pathway Diagram
 Signaling Pathways Regulating Pluripotency Of Stem Cells antibodies  Signaling Pathways Regulating Pluripotency Of Stem Cells Diagram

Diseases associated with Bmpr1a elisa kit

 Disease Name  Pubmed Publications
 Juvenile polyposis syndrome Antibodies  >49 publications with Bmpr1a and Juvenile polyposis syndrome
 Heart Defects, Congenital Antibodies  >14 publications with Bmpr1a and Heart Defects, Congenital
 Chromosome Aberrations Antibodies  >14 publications with Bmpr1a and Chromosome Aberrations
 Vascular Diseases Antibodies  >13 publications with Bmpr1a and Vascular Diseases
 Breast Neoplasms Antibodies  >12 publications with Bmpr1a and Breast Neoplasms
 Craniofacial Abnormalities Antibodies  >12 publications with Bmpr1a and Craniofacial Abnormalities
 Hamartoma Syndrome, Multiple Antibodies  >11 publications with Bmpr1a and Hamartoma Syndrome, Multiple
 Hyperplasia Antibodies  >10 publications with Bmpr1a and Hyperplasia
 Female Urogenital Diseases Antibodies  >10 publications with Bmpr1a and Female Urogenital Diseases
 Abnormalities, Multiple Antibodies  >10 publications with Bmpr1a and Abnormalities, Multiple

Organs/Tissues associated with Bmpr1a elisa kit

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >69 publications with Bmpr1a and Embryonic Tissue
 Brain Antibodies  >30 publications with Bmpr1a and Brain
 Ovary Antibodies  >20 publications with Bmpr1a and Ovary
 Lung Antibodies  >16 publications with Bmpr1a and Lung
 Prostate Antibodies  >6 publications with Bmpr1a and Prostate
 Pancreas Antibodies  >5 publications with Bmpr1a and Pancreas
 Spleen Antibodies  >1 publications with Bmpr1a and Spleen
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