Rabbit Anti-PIN1 Polyclonal Antibody – Cat# MBS7006852

Immunohistochemistry of paraffin-embedded human testis tissue using MBS7006852 at dilution of 1:100

PIN1 Antibody – Rabbit Polyclonal

Name: PIN1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS7006852
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7006852

Peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated Ser/Thr-Pro (pSer/Thr-Pro) motifs in a subset of proteins, resulting in conformational changes in the proteins (PubMed:21497122, PubMed:22033920). Displays a… More details

$230 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PIN1, Polyclonal Antibody

Full Product Name

PIN1 Antibody

Product Gene Name

anti-PIN1 antibody

Product Synonym Names

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC:5.2.1.8); PIN1; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; Rotamase Pin1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid

Purity/Purification

Affinity Purified

Preparation and Storage

Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Matching Pairs

Unconjugated Antibody: PIN1 (MBS7006852)
HRP Conjugated Antibody: PIN1 (MBS1492081)

Matching Pairs

Unconjugated Antibody: PIN1 (MBS7006852)
FITC Conjugated Antibody: PIN1 (MBS1492358)

Molecular Weight

18,243 Da

OMIM

601052

3D Structure

ModBase 3D Structure for Q13526

Immunogen

Recombinant human Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 protein

Conjugation

Non-conjugated

Storage Buffer

Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Santa Cruz Alternative

Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7413 / sc-7409 / sc-7412 / sc-15340

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-PIN1 antibody

ELISA (EIA), Immunohistochemistry (IHC)

Application Notes for anti-PIN1 antibody

Recommended dilution: IHC: 1:20-1:200

Other Notes

Small volumes of anti-PIN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PIN1 purchase

MBS7006852 is an antibody targeting PIN1. Also known as PIN1 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PIN1. It may not necessarily be applicable to this product.

NCBI GI #

5453898

NCBI GeneID

5300

NCBI Accession #

NP_006212.1

UniProt Primary Accession #

Q13526

UniProt Secondary Accession #

Q53X75; A8K4V9

UniProt Related Accession #

Q13526

GenBank Nucleotide #

NM_006221.3

NCBI Official Full Name

peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

NCBI Official Synonym Full Names

peptidylprolyl cis/trans isomerase, NIMA-interacting 1

NCBI Official Symbol

PIN1

NCBI Official Synonym Symbols

DOD; UBL5

UniProt Protein Name

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

UniProt Synonym Protein Names

Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; Rotamase Pin1

Protein Family

Auxin efflux carrier component

UniProt Gene Name

PIN1

UniProt Synonym Gene Names

PPIase Pin1

UniProt Entry Name

PIN1_HUMAN

NCBI Protein Information

peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

NCBI Summary for PIN1

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]

Research Articles on PIN1

1. These findings suggest the potential effectiveness of Pin1 inhibitors as therapeutic agents for prostate cancers, regardless of their androgen sensitivity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PIN1 antibody

Reference Product	PubMed Publications
MYC antibody	>31 publications with PIN1 and MYC
PML antibody	>11 publications with PIN1 and PML
CDC25C antibody	>9 publications with PIN1 and CDC25C
CDK1 antibody	>8 publications with PIN1 and CDK1
TP53 antibody	>7 publications with PIN1 and TP53
BCL2 antibody	>5 publications with PIN1 and BCL2
BRAF antibody	>2 publications with PIN1 and BRAF
RAF1 antibody	>2 publications with PIN1 and RAF1
PPP2CA antibody	>1 publications with PIN1 and PPP2CA

Diseases associated with anti-PIN1 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>104 publications with PIN1 and Nervous System Diseases
Brain Diseases Antibodies	>100 publications with PIN1 and Brain Diseases
Breast Neoplasms Antibodies	>66 publications with PIN1 and Breast Neoplasms
Cell Transformation, Neoplastic Antibodies	>46 publications with PIN1 and Cell Transformation, Neoplastic
Inflammation Antibodies	>25 publications with PIN1 and Inflammation
Liver Diseases Antibodies	>23 publications with PIN1 and Liver Diseases
Neoplasm Metastasis Antibodies	>19 publications with PIN1 and Neoplasm Metastasis
Carcinoma, Hepatocellular Antibodies	>18 publications with PIN1 and Carcinoma, Hepatocellular
Lung Neoplasms Antibodies	>17 publications with PIN1 and Lung Neoplasms
Necrosis Antibodies	>17 publications with PIN1 and Necrosis

Organs/Tissues associated with anti-PIN1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>97 publications with PIN1 and Brain
Blood Antibodies	>53 publications with PIN1 and Blood
Lung Antibodies	>36 publications with PIN1 and Lung
Liver Antibodies	>31 publications with PIN1 and Liver
Prostate Antibodies	>25 publications with PIN1 and Prostate
Nerve Antibodies	>25 publications with PIN1 and Nerve
Kidney Antibodies	>20 publications with PIN1 and Kidney
Embryonic Tissue Antibodies	>18 publications with PIN1 and Embryonic Tissue
Bone Antibodies	>18 publications with PIN1 and Bone
Muscle Antibodies	>15 publications with PIN1 and Muscle