Hamster APOC3 ELISA Kit – Cat# MBS031368

Apolipoprotein C3 (APOC3) ELISA Kit for Hamster

Name: Hamster APOC3 ELISA Kit; Apolipoprotein C3; MyBioSource
Brand: MyBioSource
SKU: MBS031368
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS031368

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of APOC3 (hereafter termed "analyte") in… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Apolipoprotein C3 (APOC3), ELISA Kit

Full Product Name

Hamster Apolipoprotein C3 ELISA Kit

Product Gene Name

APOC3 elisa kit

Species Reactivity

Hamster

Assay Type

Quantitative Sandwich

Detection Range

15.6ug/ml-500ug/ml

Sensitivity

2.0ug/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

10,852 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (116700624..116703787). Location: 11q23.3

OMIM

107720

3D Structure

ModBase 3D Structure for P02656

Other Notes

Small volumes of APOC3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APOC3 purchase

MBS031368 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Apolipoprotein C3 (APOC3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing APOC3. The ELISA analytical biochemical technique of the MBS031368 kit is based on APOC3 antibody-APOC3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect APOC3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, APOC3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for APOC3. It may not necessarily be applicable to this product.

NCBI GI #

4557323

NCBI GeneID

345

NCBI Accession #

NP_000031.1

UniProt Primary Accession #

P02656

UniProt Secondary Accession #

Q08E83; Q6Q786

UniProt Related Accession #

P02656

GenBank Nucleotide #

NM_000040.1

NCBI Official Full Name

apolipoprotein C-III

NCBI Official Synonym Full Names

apolipoprotein C-III

NCBI Official Symbol

APOC3

NCBI Official Synonym Symbols

HALP2; APOCIII

UniProt Protein Name

Apolipoprotein C-III

UniProt Synonym Protein Names

Apolipoprotein C3

Protein Family

Apolipoprotein

UniProt Gene Name

APOC3

UniProt Synonym Gene Names

Apo-CIII; ApoC-III

UniProt Entry Name

APOC3_HUMAN

NCBI Protein Information

apolipoprotein C-III; apo-CIII; apoC-III; apolipoprotein C3

NCBI Summary for APOC3

Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia. [provided by RefSeq, Jul 2008]

UniProt Comments for APOC3

APOC3: Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles. Defects in APOC3 are the cause of hyperalphalipoproteinemia type 2 (HALP2). HALP2 is a condition characterized by high levels of high density lipoprotein (HDL) and increased HDL cholesterol levels. Belongs to the apolipoprotein C3 family.

Protein type: Secreted, signal peptide; Lipid-binding; Secreted

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: extracellular space; chylomicron; early endosome; extracellular region

Molecular Function: lipase inhibitor activity; cholesterol binding; phospholipid binding; enzyme regulator activity

Biological Process: response to drug; response to peptide hormone stimulus; phototransduction, visible light; cholesterol metabolic process; regulation of Cdc42 protein signal transduction; lipoprotein metabolic process; cholesterol efflux; G-protein coupled receptor protein signaling pathway; cholesterol homeostasis; reverse cholesterol transport; triacylglycerol metabolic process; phospholipid efflux; negative regulation of lipid catabolic process; lipoprotein transport; triacylglycerol catabolic process; negative regulation of receptor-mediated endocytosis; negative regulation of lipoprotein lipase activity; inflammatory response; negative regulation of lipid metabolic process; triacylglycerol mobilization; retinoid metabolic process; response to nutrient; negative regulation of fatty acid biosynthetic process

Disease: Apolipoprotein C-iii Deficiency

Research Articles on APOC3

1. Measurement of plasma ApoCIII may improve CAD prediction in the general population

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with APOC3 elisa kit

Reference Product	PubMed Publications
APOE elisa kit	>63 publications with APOC3 and APOE
APOA5 elisa kit	>60 publications with APOC3 and APOA5
APOA1 elisa kit	>58 publications with APOC3 and APOA1
LPL elisa kit	>46 publications with APOC3 and LPL
APOB elisa kit	>44 publications with APOC3 and APOB
APOA4 elisa kit	>37 publications with APOC3 and APOA4
APOC2 elisa kit	>11 publications with APOC3 and APOC2
APOA2 elisa kit	>8 publications with APOC3 and APOA2
PPARG elisa kit	>5 publications with APOC3 and PPARG
INS elisa kit	>2 publications with APOC3 and INS

Pathways associated with APOC3 elisa kit

Products by Pathway	Pathway Diagram
Chylomicron-mediated Lipid Transport Pathway antibodies	Chylomicron-mediated Lipid Transport Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Diseases Associated With Visual Transduction Pathway antibodies	Diseases Associated With Visual Transduction Pathway Diagram
HDL-mediated Lipid Transport Pathway antibodies	HDL-mediated Lipid Transport Pathway Diagram
Lipid Digestion, Mobilization, And Transport Pathway antibodies	Lipid Digestion, Mobilization, And Transport Pathway Diagram
Lipoprotein Metabolism Pathway antibodies	Lipoprotein Metabolism Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
PPAR Signaling Pathway antibodies	PPAR Signaling Pathway Diagram
PPAR Signaling Pathway antibodies	PPAR Signaling Pathway Diagram

Diseases associated with APOC3 elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>71 publications with APOC3 and Cardiovascular Diseases
Coronary Disease Antibodies	>48 publications with APOC3 and Coronary Disease
Hypertriglyceridemia Antibodies	>44 publications with APOC3 and Hypertriglyceridemia
Dyslipidemias Antibodies	>44 publications with APOC3 and Dyslipidemias
Heart Diseases Antibodies	>44 publications with APOC3 and Heart Diseases
Hyperlipidemias Antibodies	>36 publications with APOC3 and Hyperlipidemias
Atherosclerosis Antibodies	>33 publications with APOC3 and Atherosclerosis
Insulin Resistance Antibodies	>32 publications with APOC3 and Insulin Resistance
Obesity Antibodies	>28 publications with APOC3 and Obesity
Hyperinsulinism Antibodies	>26 publications with APOC3 and Hyperinsulinism

Organs/Tissues associated with APOC3 elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>41 publications with APOC3 and Liver
Heart Antibodies	>36 publications with APOC3 and Heart
Connective Tissue Antibodies	>7 publications with APOC3 and Connective Tissue
Kidney Antibodies	>4 publications with APOC3 and Kidney
Muscle Antibodies	>2 publications with APOC3 and Muscle
Brain Antibodies	>2 publications with APOC3 and Brain
Lung Antibodies	>1 publications with APOC3 and Lung