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ASCL2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3200714

This is a rabbit polyclonal antibody against ASCL2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
ASCL2, Polyclonal Antibody
Full Product Name
ASCL2 antibody - middle region
Product Gene Name
Product Synonym Gene Name
ASH2; HASH2; MASH2; bHLHa45
Immunogen Sequence
Synthetic peptide located within the following region: QALRQHVPHG GASKKLSKVE TLRSAVEYIR ALQRLLAEHD AVRNALAGGL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat, Zebrafish
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
ASCL2 peptide (MBS3225756) is used for blocking the activity of ASCL2 antibody (MBS3200714)
Molecular Weight
20kDa
OMIM
601886
3D Structure
ModBase 3D Structure for Q99929
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 92%; Rabbit: 77%; Rat: 100%; Zebrafish: 77%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ASCL2
Applications Tested/Suitable for anti-ASCL2 antibody
Western Blot (WB)

Western Blot (WB) of anti-ASCL2 antibody

WB Suggested Anti-ASCL2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: DU145 cell lysate
Rabbit Anti-ASCL2 Polyclonal Antibody – Cat# MBS3200714

Other Notes

Small volumes of anti-ASCL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASCL2 purchase

MBS3200714 is an antibody targeting ASCL2. Also known as ASCL2 antibody - middle region. Reactive in Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ASCL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
achaete-scute homolog 2
NCBI Official Synonym Full Names
achaete-scute family bHLH transcription factor 2
NCBI Official Symbol
ASCL2
NCBI Official Synonym Symbols
ASH2; HASH2; MASH2; bHLHa45
UniProt Protein Name
Achaete-scute homolog 2
UniProt Synonym Protein Names
Class A basic helix-loop-helix protein 45; bHLHa45; Mash2
Protein Family
UniProt Gene Name
ASCL2
UniProt Synonym Gene Names
BHLHA45; HASH2; ASH-2; hASH2; bHLHa45
UniProt Entry Name
ASCL2_HUMAN
NCBI Protein Information
achaete-scute homolog 2

NCBI Summary for ASCL2

This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008]
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UniProt Comments for ASCL2

ASCL2: a basic helix-loop-helix transcription factor, plays an essential role in the maintenance of adult intestinal stem cells

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: cytoplasm; nucleus

Molecular Function: protein dimerization activity; transcription factor activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; somatic stem cell maintenance; response to hypoxia; negative regulation of transcription from RNA polymerase II promoter; placenta development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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