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SCD Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3201173

This is a rabbit polyclonal antibody against SCD. It was validated on Western Blot and immunohistochemistryTarget Description: Stearoyl-CoA desaturase ( fatty acid desaturase, SCD) is expressed at high levels in several human tissues and is required for the… More details

$440 / 0.1 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SCD, Polyclonal Antibody
Full Product Name
SCD antibody - middle region
Product Gene Name
Product Synonym Gene Name
SCD1; FADS5; SCDOS; MSTP008
Immunogen Sequence
Synthetic peptide located within the following region: HPAVKEKGST LDLSDLEAEK LVMFQRRYYK PGLLMMCFIL PTLVPWYFWG
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Goat, Guinea Pig, Human, Sheep
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Protein A purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
SCD peptide (MBS3226199) is used for blocking the activity of SCD antibody (MBS3201173)
Molecular Weight
41kDa
OMIM
604031
3D Structure
ModBase 3D Structure for O00767
Homology
Cow: 92%; Dog: 85%; Goat: 85%; Guinea Pig: 85%; Human: 100%; Mouse: 77%; Rat: 77%; Sheep: 85%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SCD

Product Categories/Family for anti-SCD antibody

Applications Tested/Suitable for anti-SCD antibody
Immunohistochemistry (IHC), Western Blot (WB)

Immunohistochemistry (IHC) of anti-SCD antibody

Human Liver
Rabbit Anti-SCD Polyclonal Antibody – Cat# MBS3201173

Western Blot (WB) of anti-SCD antibody

Host: Rabbit
Target Name: SCD
Sample Tissue: Human Jurkat
Antibody Dilution: 1.0ug/ml
Rabbit Anti-SCD Polyclonal Antibody, Western Blot (WB) – Cat# MBS3201173

Western Blot (WB) of anti-SCD antibody

WB Suggested Anti-SCD Antibody Titration: 1.0ug/ml
Positive Control: Human Liver
Rabbit Anti-SCD Polyclonal Antibody, Western Blot (WB) – Cat# MBS3201173

Other Notes

Small volumes of anti-SCD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCD purchase

MBS3201173 is an antibody targeting SCD. Also known as SCD antibody - middle region. Reactive in Cow, Dog, Goat, Guinea Pig, Human, Sheep. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SCD. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
acyl-CoA desaturase
NCBI Official Synonym Full Names
stearoyl-CoA desaturase
NCBI Official Symbol
SCD
NCBI Official Synonym Symbols
SCD1; FADS5; SCDOS; hSCD1; MSTP008
UniProt Protein Name
Acyl-CoA desaturase
UniProt Synonym Protein Names
Delta(9)-desaturase; Delta-9 desaturase; Fatty acid desaturase; Stearoyl-CoA desaturase
Protein Family
UniProt Gene Name
SCD
UniProt Synonym Gene Names
Delta-9 desaturase
UniProt Entry Name
ACOD_HUMAN
NCBI Protein Information
acyl-CoA desaturase

NCBI Summary for SCD

This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015]
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UniProt Comments for SCD

SCD: Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Belongs to the fatty acid desaturase family.

Protein type: Lipid Metabolism - unsaturated fatty acid biosynthesis; Membrane protein, multi-pass; Endoplasmic reticulum; Oxidoreductase; Membrane protein, integral; EC 1.14.19.1

Chromosomal Location of Human Ortholog: 10q24.31

Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane

Molecular Function: iron ion binding; stearoyl-CoA 9-desaturase activity

Biological Process: fatty acid biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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