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CDKN2AIP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3205518

This is a rabbit polyclonal antibody against CARF. It was validated on Western Blot and immunohistochemistryTarget Description: CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the… More details

$440 / 0.1 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CARF (CDKN2AIP), Polyclonal Antibody
Full Product Name
CARF antibody - C-terminal region
Product Gene Name
Product Synonym Gene Name
CARF
Immunogen Sequence
Synthetic peptide located within the following region: AIEALKATLD VFFVPLKELA DLPQNKSSQE SIVCELRCKS VYLGTGCGKS
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Protein A purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
CARF peptide (MBS3230481) is used for blocking the activity of CARF antibody (MBS3205518)
Molecular Weight
64kDa
3D Structure
ModBase 3D Structure for Q9NXV6
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CARF
Applications Tested/Suitable for anti-CDKN2AIP antibody
Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-CDKN2AIP antibody

WB Suggested Anti-CARF Antibody Titration: 0.3125ug/ml
Positive Control: Jurkat cell lysateCDKN2AIP is supported by BioGPS gene expression data to be expressed in Jurkat
Rabbit Anti-CDKN2AIP Polyclonal Antibody – Cat# MBS3205518

Other Notes

Small volumes of anti-CDKN2AIP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDKN2AIP purchase

MBS3205518 is an antibody targeting CDKN2AIP. Also known as CARF antibody - C-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CDKN2AIP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
CDKN2A-interacting protein isoform 1
NCBI Official Synonym Full Names
CDKN2A interacting protein
NCBI Official Symbol
CDKN2AIP
NCBI Official Synonym Symbols
CARF
UniProt Protein Name
CDKN2A-interacting protein
UniProt Synonym Protein Names
Collaborator of ARF
UniProt Gene Name
CDKN2AIP
UniProt Synonym Gene Names
CARF
UniProt Entry Name
CARF_HUMAN
NCBI Protein Information
CDKN2A-interacting protein

NCBI Summary for CDKN2AIP

The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
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UniProt Comments for CDKN2AIP

CDKN2AIP: co-localizes and interacts with p14ARF in the nucleolus. Co-regulated with ARF and cooperates with it in activating p53.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 4q35.1

Cellular Component: nucleoplasm; granular component; cytoplasm; nucleolus; nucleus

Molecular Function: protein binding; RNA binding; p53 binding

Biological Process: positive regulation of signal transduction; regulation of protein stability; negative regulation of cell growth; response to DNA damage stimulus; positive regulation of cell growth
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-CDKN2AIP antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with CDKN2AIP and Nerve
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