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CD133 Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS856765

PROM1, also named as PROML1, CD133 and AC133, belongs to the prominin family. PROM1 interacts with PCDH21 and with actin filaments. CD133 is a cance stem cell marker. Defects in PROM1 are the cause of retinitis pigmentosa type 41 (RP41)which also known as… More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD133, Antibody
Full Product Name
CD133 Antibody
Product Gene Name
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Each vial at least contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.1% sodium azide.
Purity/Purification
Affinity Purification
Preparation and Storage
Store at 4 degree C or-20 degree C (with 50% glycerol); Minimize freeze-thaw cycles; Non-hazardous.
Molecular Weight
94,605 Da
OMIM
603786
3D Structure
ModBase 3D Structure for O43490
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CD133 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CD133 antibody
WB: 1:500-1000

Testing Data of anti-CD133 antibody

Rabbit Anti-CD133 Antibody – Cat# MBS856765

Other Notes

Small volumes of anti-CD133 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD133 purchase

MBS856765 is an antibody targeting CD133. Also known as CD133 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CD133. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
prominin-1 isoform 2
NCBI Official Synonym Full Names
prominin 1
NCBI Official Symbol
PROM1
NCBI Official Synonym Symbols
RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061
UniProt Protein Name
Prominin-1
UniProt Synonym Protein Names
Antigen AC133; Prominin-like protein 1; CD_antigen: CD133
Protein Family
UniProt Gene Name
PROM1
UniProt Synonym Gene Names
PROML1
NCBI Protein Information
prominin-1

NCBI Summary for CD133

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
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UniProt Comments for CD133

May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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