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ADCY6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3208439

This is a rabbit polyclonal antibody against ADCY6. It was validated on Western Blot using a cell lysate as a positive control.Target Description: ADCY6 is adenylate cyclase 6, which is a membrane-associated enzyme and catalyzes the formation of the secondary… More details

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Product Overview

Online Datasheet in PDF
Product Name
ADCY6, Polyclonal Antibody
Full Product Name
ADCY6 antibody - C-terminal region
Product Gene Name
anti-ADCY6 antibody
Product Synonym Gene Name
DKFZp779F075; KIAA0422; AC6
Immunogen Sequence
Synthetic peptide located within the following region: LIYLVLLLLG PPATIFDNYD LLLGVHGLAS SNETFDGLDC PAAGRVALKY
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
ADCY6 peptide (MBS3233401) is used for blocking the activity of ADCY6 antibody (MBS3208439)
Molecular Weight
125kDa
OMIM
600294
3D Structure
ModBase 3D Structure for O43306
Homology
Cow: 100%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human ADCY6

Product Categories/Family for anti-ADCY6 antibody

Polyclonal; Lymphocyte Signaling; Membrane Protein; Drugs and Drug Metabolism; Membrane & Traffic; GPCR
Applications Tested/Suitable for anti-ADCY6 antibody
Western Blot (WB)

Western Blot (WB) of anti-ADCY6 antibody

Host: Rabbit
Target Name: ADCY6
Sample Tissue: Human Fetal Kidney
Antibody Dilution: 1.0ug/ml
Rabbit Anti-ADCY6 Polyclonal Antibody – Cat# MBS3208439

Western Blot (WB) of anti-ADCY6 antibody

WB Suggested Anti-ADCY6 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Hela cell lysate
Rabbit Anti-ADCY6 Polyclonal Antibody, Western Blot (WB) – Cat# MBS3208439

Other Notes

Small volumes of anti-ADCY6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ADCY6 purchase

MBS3208439 is an antibody targeting ADCY6. Also known as ADCY6 antibody - C-terminal region. Reactive in Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ADCY6. It may not necessarily be applicable to this product.

NCBI GI #
10947061
NCBI GeneID
112
NCBI Accession #
NP_066193
UniProt Primary Accession #
O43306
UniProt Related Accession #
O43306
GenBank Nucleotide #
NM_020983
NCBI Official Synonym Full Names
adenylate cyclase 6
NCBI Official Symbol
ADCY6
NCBI Official Synonym Symbols
AC6; LCCS8
UniProt Protein Name
Adenylate cyclase type 6
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 6; Adenylate cyclase type VI; Adenylyl cyclase 6; Ca(2+)-inhibitable adenylyl cyclase
Protein Family
Adenylate cyclase
UniProt Gene Name
ADCY6
UniProt Synonym Gene Names
KIAA0422
UniProt Entry Name
ADCY6_HUMAN
NCBI Protein Information
adenylate cyclase type 6

NCBI Summary for ADCY6

This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita. [provided by RefSeq, May 2015]
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Research Articles on ADCY6

1. rs3730071G/T and rs77913913G/T of ADCY6 were non-polymorphic with respect to HAPE.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ADCY6 antibody

 Reference Product  PubMed Publications
 ADRB2 antibody  >2 publications with ADCY6 and ADRB2

Pathways associated with anti-ADCY6 antibody

 Products by Pathway  Pathway Diagram
 Activation Of GABAB Receptors Pathway antibodies  Activation Of GABAB Receptors Pathway Diagram
 Adenylate Cyclase Activating Pathway antibodies  Adenylate Cyclase Activating Pathway Diagram
 Adenylate Cyclase Inhibitory Pathway antibodies  Adenylate Cyclase Inhibitory Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Ca-dependent Events Pathway antibodies  Ca-dependent Events Pathway Diagram
 CaM Pathway antibodies  CaM Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Calmodulin Induced Events Pathway antibodies  Calmodulin Induced Events Pathway Diagram

Diseases associated with anti-ADCY6 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with ADCY6 and Nervous System Diseases
 Neoplasms Antibodies  >1 publications with ADCY6 and Neoplasms
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