Rabbit Anti-TMC2 Polyclonal Antibody – Cat# MBS3209870

WB Suggested Anti-TMC2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Hela cell lysate

TMC2 Antibody – Rabbit Polyclonal

Name: TMC2 Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS3209870
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3209870

This is a rabbit polyclonal antibody against TMC2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: TMC2 is considered a member of transmembrane proteins family. The specific function of this gene is unknown;… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TMC2, Polyclonal Antibody

Full Product Name

TMC2 antibody - middle region

Product Gene Name

anti-TMC2 antibody

Product Synonym Gene Name

C20orf145; dJ686C3.3

Immunogen Sequence

Synthetic peptide located within the following region: YCWCWDLEAG FPSYAEFDIS GNVLGLIFNQ GMIWMGSFYA PGLVGINVLR

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity Purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

TMC2 peptide (MBS3234825) is used for blocking the activity of TMC2 antibody (MBS3209870)

Molecular Weight

102kDa

OMIM

606707

3D Structure

ModBase 3D Structure for Q8TDI7

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 85%; Rat: 100%; Zebrafish: 100%

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TMC2

Product Categories/Family for anti-TMC2 antibody

Polyclonal; Membrane Protein; Disease Related

Applications Tested/Suitable for anti-TMC2 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-TMC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TMC2 purchase

MBS3209870 is an antibody targeting TMC2. Also known as TMC2 antibody - middle region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TMC2. It may not necessarily be applicable to this product.

NCBI GI #

94536852

NCBI GeneID

117532

NCBI Accession #

NP_542789

UniProt Primary Accession #

Q8TDI7

UniProt Related Accession #

Q8TDI7

GenBank Nucleotide #

NM_080751

NCBI Official Full Name

transmembrane channel-like protein 2

NCBI Official Synonym Full Names

transmembrane channel like 2

NCBI Official Symbol

TMC2

NCBI Official Synonym Symbols

C20orf145

UniProt Protein Name

Transmembrane channel-like protein 2

UniProt Synonym Protein Names

Transmembrane cochlear-expressed protein 2

UniProt Gene Name

TMC2

UniProt Synonym Gene Names

C20orf145; UNQ907/PRO1928

UniProt Entry Name

TMC2_HUMAN

NCBI Protein Information

transmembrane channel-like protein 2

NCBI Summary for TMC2

This gene encodes a transmembrane protein that is necesssary for mechanotransduction in cochlear hair cells of the inner ear. Mutations in this gene may underlie hereditary disorders of balance and hearing. [provided by RefSeq, Aug 2015]

Research Articles on TMC2

1. But the great majority of evidence is consistent with these TMCs as pore-forming subunits of the long-sought hair-cell transduction channel. [review]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TMC2 antibody

Disease Name	Pubmed Publications
Neurologic Manifestations Antibodies	>10 publications with TMC2 and Neurologic Manifestations

Organs/Tissues associated with anti-TMC2 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with TMC2 and Brain