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SMS Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3215852

This is a rabbit polyclonal antibody against SMS. It was validated on Western BlotTarget Description: The protein encoded by this gene belongs to the spermidine/spermine synthases family. This gene encodes an ubiquitous enzyme of polyamine metabolism. More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SMS, Polyclonal Antibody
Full Product Name
SMS antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
MRSR; SPMSY; SRS; SpS
Immunogen Sequence
Synthetic peptide located within the following region: DGDAQGKEEI DSILNKVEER MKELSQDSTG RVKRLPPIVR GGAIDRYWPT
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
SMS peptide (MBS3240754) is used for blocking the activity of SMS antibody (MBS3215852)
Molecular Weight
40kDa
OMIM
300105
3D Structure
ModBase 3D Structure for P52788
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%
Applications Tested/Suitable for anti-SMS antibody
Western Blot (WB)

Western Blot (WB) of anti-SMS antibody

WB Suggested Anti-SMS Antibody
Titration: 1.0 ug/ml
Positive Control: MCF7 Whole Cell
Rabbit Anti-SMS Polyclonal Antibody – Cat# MBS3215852

Other Notes

Small volumes of anti-SMS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SMS purchase

MBS3215852 is an antibody targeting SMS. Also known as SMS antibody - N-terminal region. Reactive in Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SMS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
spermine synthase isoform 1
NCBI Official Synonym Full Names
spermine synthase
NCBI Official Symbol
SMS
NCBI Official Synonym Symbols
SRS; SpS; MRSR; SPMSY
UniProt Protein Name
Spermine synthase
UniProt Synonym Protein Names
Spermidine aminopropyltransferase
Protein Family
UniProt Gene Name
SMS
UniProt Synonym Gene Names
SPMSY
UniProt Entry Name
SPSY_HUMAN
NCBI Protein Information
spermine synthase

NCBI Summary for SMS

This gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson Syndrome (SRS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
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UniProt Comments for SMS

SMS: an ubiquitous enzyme of polyamine metabolism. Synthesizes spermine from spermidine.

Protein type: EC 2.5.1.22; Other Amino Acids Metabolism - beta-alanine; Amino Acid Metabolism - cysteine and methionine; Transferase; Other Amino Acids Metabolism - glutathione; Amino Acid Metabolism - arginine and proline

Chromosomal Location of Human Ortholog: Xp22.1

Cellular Component: cytosol

Molecular Function: spermidine synthase activity; spermine synthase activity

Biological Process: methionine metabolic process; spermine biosynthetic process; polyamine metabolic process

Disease: Mental Retardation, X-linked, Syndromic, Snyder-robinson Type
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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