Rabbit Anti-ARHGAP5 Polyclonal Antibody – Cat# MBS3220177

Host: Rabbit
Target Name: RHG05
Sample Type: HepG2 Whole Cell lysates
Antibody Dilution: 1.0ug/ml

ARHGAP5 Antibody – Rabbit Polyclonal

Name: ARHGAP5 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS3220177
Price: 490 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3220177

This is a rabbit polyclonal antibody against RHG05. It was validated on Western BlotTarget Description: Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound… More details

$490 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ARHGAP5, Polyclonal Antibody

Full Product Name

ARHGAP5 Antibody - C-terminal region

Product Gene Name

anti-ARHGAP5 antibody

Product Synonym Gene Name

GFI2; p190-B; RhoGAP5; p190BRhoGAP

Immunogen Sequence

Synthetic peptide located within the following region: YLSDNTREST HQSEDVFLPS PRDCFPYNNY PDSDDDTEAP PPYSPIGDDV

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Purity/Purification

Affinity purified

Preparation and Storage

For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

ARHGAP5 peptide (MBS3245000) is used for blocking the activity of ARHGAP5 antibody (MBS3220177)

Molecular Weight

165kDa

OMIM

602680

3D Structure

ModBase 3D Structure for Q13017

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human RHG05

Product Categories/Family for anti-ARHGAP5 antibody

Polyclonal; Various

Applications Tested/Suitable for anti-ARHGAP5 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-ARHGAP5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARHGAP5 purchase

MBS3220177 is an antibody targeting ARHGAP5. Also known as ARHGAP5 Antibody - C-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARHGAP5. It may not necessarily be applicable to this product.

NCBI GI #

530403725

NCBI GeneID

394

NCBI Accession #

XP_005267693

UniProt Primary Accession #

Q13017

UniProt Related Accession #

Q13017

GenBank Nucleotide #

XM_005267636.4

NCBI Official Full Name

rho GTPase-activating protein 5 isoform X1

NCBI Official Synonym Full Names

Rho GTPase activating protein 5

NCBI Official Symbol

ARHGAP5

NCBI Official Synonym Symbols

GFI2; p190-B; RhoGAP5; p190BRhoGAP

UniProt Protein Name

Rho GTPase-activating protein 5

UniProt Synonym Protein Names

Rho-type GTPase-activating protein 5; p190-B

Protein Family

Putative uncharacterized protein

UniProt Gene Name

ARHGAP5

UniProt Synonym Gene Names

RHOGAP5

UniProt Entry Name

RHG05_HUMAN

NCBI Protein Information

rho GTPase-activating protein 5

NCBI Summary for ARHGAP5

Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for ARHGAP5

ARHGAP5: a GTPase activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of p120GAP. Negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP.

Protein type: GAPs; Motility/polarity/chemotaxis; GAPs, Rac/Rho

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: membrane; cytoplasm; cytosol

Molecular Function: GTPase activity; protein binding; GTP binding; SH2 domain binding

Biological Process: regulation of small GTPase mediated signal transduction; mammary gland development; metabolic process; small GTPase mediated signal transduction; positive regulation of mesenchymal cell proliferation; cell adhesion; regulation of cell size; Rho protein signal transduction; positive regulation of cell migration

Research Articles on ARHGAP5

1. only collagen-IV elicits the formation of proteolytically active podosomes through a mechanism involving increased Src phosphorylation, p190RhoGAP-B (also known as ARHGAP5) relocalisation and MT1-MMP (also known as MMP14) cell surface exposure at podosome sites.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.