Mouse Anti-LPL Monoclonal Antibody – Cat# MBS330109

LPL Antibody – Mouse Monoclonal

Name: LPL Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS330109
Price: 375 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS330109

MBS330109 is an antibody targeting LPL. Also known as Anti-LPL mAb. Host: Mouse. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

LPL, Monoclonal Antibody

Full Product Name

Anti-LPL mAb

Product Gene Name

anti-LPL antibody

Product Synonym Names

Anti-LPL Monoclonal Antibody (Mouse Monoclonal (IgG1))

Clonality

Monoclonal

Clone Number

LPL.A4

Host

Mouse

Form/Format

1mg/ml in PBS, pH 7.4 with 0.05% sodium azide. Frozen liquid.

Specificity

Recognize specifically LPL from human and bovine.

Preparation and Storage

Stable for one year at -20 degree C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Aliquot will be stable at 4 degree C for 3 months.

Molecular Weight

53,213 Da

Chromosome Location

Chromosome: 8; NC_000008.10 (19796582..19824770). Location: 8p22

3D Structure

ModBase 3D Structure for Q6IAV0

Immunogen

Human LPL whole protein

Product Categories/Family for anti-LPL antibody

Antibodies for Lipid/Lipo Protein Metabolism Research

Applications Tested/Suitable for anti-LPL antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-LPL antibody

Western blot (1:100-1:250) and ELISA (1:2000~5000) in lipid metabolic research. Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF) secretion and induction of vascular smooth muscle cell proliferation.

Other Notes

Small volumes of anti-LPL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LPL. It may not necessarily be applicable to this product.

NCBI GI #

48146225

NCBI GeneID

4023

NCBI Accession #

CAG33335.1

UniProt Primary Accession #

Q6IAV0

UniProt Related Accession #

P06858

NCBI Official Full Name

LPL

NCBI Official Synonym Full Names

lipoprotein lipase

NCBI Official Symbol

LPL

NCBI Official Synonym Symbols

LIPD; HDLCQ11

UniProt Protein Name

LPL protein

Protein Family

Lipoprotein

UniProt Gene Name

LPL

UniProt Entry Name

Q6IAV0_HUMAN

NCBI Protein Information

lipoprotein lipase

NCBI Summary for LPL

LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]

UniProt Comments for LPL

Sequence similarities: Belongs to the AB hydrolase superfamily. Lipase family. RuleBase RU004262

Research Articles on LPL

1. A polymorphism in the GPIHBP1 gene promoter was associated with an increased risk of hypertriglyceridemia and had an additive effect on the risk conferred by LPL defective alleles.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-LPL antibody

Products by Pathway	Pathway Diagram
Adipogenesis Pathway antibodies	Adipogenesis Pathway Diagram
Alzheimer's Disease Pathway antibodies	Alzheimer's Disease Pathway Diagram
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Alzheimers Disease Pathway antibodies	Alzheimers Disease Pathway Diagram
Chylomicron-mediated Lipid Transport Pathway antibodies	Chylomicron-mediated Lipid Transport Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Diseases Associated With Visual Transduction Pathway antibodies	Diseases Associated With Visual Transduction Pathway Diagram
Fatty Acid Beta Oxidation Pathway antibodies	Fatty Acid Beta Oxidation Pathway Diagram
Glycerolipid Metabolism Pathway antibodies	Glycerolipid Metabolism Pathway Diagram

Organs/Tissues associated with anti-LPL antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>2306 publications with LPL and Blood
Adipose Tissue Antibodies	>1209 publications with LPL and Adipose Tissue
Connective Tissue Antibodies	>909 publications with LPL and Connective Tissue
Liver Antibodies	>850 publications with LPL and Liver
Muscle Antibodies	>790 publications with LPL and Muscle
Heart Antibodies	>610 publications with LPL and Heart
Vascular Antibodies	>388 publications with LPL and Vascular
Intestine Antibodies	>216 publications with LPL and Intestine
Bone Antibodies	>156 publications with LPL and Bone
Kidney Antibodies	>153 publications with LPL and Kidney