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IL-17A Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS335089

This biotinylated Antibody can be used as Detection in a human sandwich immunoassay . The suggested coating concentration range should be optimized by each laboratory for each application. More details

$505 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-17A, Monoclonal Antibody
Full Product Name
Mouse Anti-Human IL-17A Detection Antibody, Biotin Conjugated Clone B-B51
Product Gene Name
Product Synonym Names
Anti-Human IL-17A Detection Antibody
Clonality
Monoclonal
Isotype
Mouse IgG2b Kappa light chain
Clone Number
B-B51
Host
Mouse
Form/Format
Phosphate-buffered saline. With 1% BSA and 0.09% Sodium Azide
Specificity
Recognises both natural and recombinant IL-17A
Preparation and Storage
Store at +2-8 degree C for 12 months
Matching Pairs
Biotin Conjugated Antibody: IL-17A Clone #B-B51 (MBS335089)
Unconjugated Azide Free Antibody: IL-17A Clone #B-B51 (MBS335206)
Matching Pairs
Chromosome Location
Chromosome: 6; NC_000006.11 (52051185..52055436). Location: 6p12
OMIM
603149
3D Structure
ModBase 3D Structure for Q16552
Target Species
Human
Hybridoma
Myeloma X63/AG.8653 x Balb/c node cells
Immunization
Recombinant human IL-17A
Applications Tested/Suitable for anti-IL-17A antibody
ELISA (EIA), ELISpot
Application Notes for anti-IL-17A antibody
ELISA/ELISpot: 0.05-0.5ug/mL

Sodium Azide is a poisonous and hazardous substance, handle and dispose of properly.

Other Notes

Small volumes of anti-IL-17A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-17A purchase

MBS335089 is an antibody targeting IL-17A. Also known as Mouse Anti-Human IL-17A Detection Antibody, Biotin Conjugated Clone B-B51. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-17A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-17A
NCBI Official Synonym Full Names
interleukin 17A
NCBI Official Symbol
IL17A
NCBI Official Synonym Symbols
IL17; CTLA8; IL-17; IL-17A
UniProt Protein Name
Interleukin-17A
UniProt Synonym Protein Names
Cytotoxic T-lymphocyte-associated antigen 8
Protein Family
UniProt Gene Name
IL17A
UniProt Synonym Gene Names
CTLA8; IL17; IL-17; IL-17A; CTLA-8
UniProt Entry Name
IL17_HUMAN
NCBI Protein Information
interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

NCBI Summary for IL-17A

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
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UniProt Comments for IL-17A

Function: Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.

Subunit structure: Homodimer. Ref.8

Subcellular location: Secreted.

Tissue specificity: Restricted to activated memory T-cells.

Post-translational modification: Found both in glycosylated and nonglycosylated forms.

Sequence similarities: Belongs to the IL-17 family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-IL-17A antibody

 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >83 publications with IL-17A and Mixed
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