Mouse Anti-LGALS8 Monoclonal Antibody – Cat# MBS335801

Galectin-8 (LGALS8) Antibody – Mouse Monoclonal

Name: LGALS8 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS335801
Price: 355 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS335801

MBS335801 is an antibody targeting LGALS8. Also known as Anti-Human Galectin-8 Azide Free. Reactive in Human. Host: Mouse. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Galectin-8 (LGALS8), Monoclonal Antibody

Full Product Name

Anti-Human Galectin-8 Azide Free

Product Gene Name

anti-LGALS8 antibody

Product Synonym Names

LGALS8; Gal-8; PCTA-1

Clonality

Monoclonal

Isotype

IgG2a Kappa light chain

Clone Number

B-Z18

Host

Mouse

Species Reactivity

Human

Form/Format

Phosphate-buffered saline. Sterile-filtered through 0.22 mum. Carrier and preservative free.

Specificity

Recognizes both natural and recombinant human galectin-8

Preparation and Storage

Stable at 2-8 degree C for 12 months. DO NOT FREEZE.

Matching Pairs

Unconjugated Azide Free Antibody: Galectin-8 Clone #B-Z18 (MBS335801)
Unconjugated Antibody: Galectin-8 Clone #B-Z18 (MBS335802)

Molecular Weight

40,397 Da

Hybridoma

Myeloma X63/AG.8653 x Balb/c node cells

Immunisation

Recombinant human Galectin-8

Applications Tested/Suitable for anti-LGALS8 antibody

Flow Cytometry (FC/FACS)

Other Notes

Small volumes of anti-LGALS8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LGALS8. It may not necessarily be applicable to this product.

NCBI GI #

6625728

NCBI Accession #

AAF19370.1

UniProt Secondary Accession #

O15215; Q5T3P5; Q5T3Q4; Q8TEV1; Q96B92; Q9BXC8; Q9H584; Q9H585; Q9UEZ6; Q9UP32; Q9UP33

NCBI Official Full Name

galectin-8

UniProt Protein Name

Galectin-8

UniProt Synonym Protein Names

Po66 carbohydrate-binding protein; Po66-CBP; Prostate carcinoma tumor antigen 11 PublicationManual assertion based on opinion iniRef.1"Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family."Su Z.-Z., Lin J., Shen R., Fisher P.E., Goldstein N.I., Fisher P.B.Proc. Natl. Acad. Sci. U.S.A. 93:7252-7257(1996) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANTS VAL-56 AND SER-184.

Protein Family

Galectin

UniProt Gene Name

LGALS8

UniProt Synonym Gene Names

Gal-8; Po66-CBP; PCTA-11 PublicationManual assertion based on opinion iniRef.1

UniProt Comments for LGALS8

Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy (PubMed:22246324, PubMed:28077878). Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture (PubMed:22246324, PubMed:28077878). Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52 (PubMed:22246324, PubMed:28077878). Required to restrict infection of bacterial invasion such as S.typhimurium (PubMed:22246324). Also required to restrict infection of Picornaviridae viruses (PubMed:28077878). Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans (PubMed:21288902).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.